What caliber? 45 colt?
This "Dirty Harry" edition is chambered in 44mag. Quoting DH: "...the most powerful handgun cartridge in the world. It'll blow your head clean off."
Of course, many more powerful HG cartridges have emerged since then: 45 Casul, 460 Ruger, 480 Ruger, 500 S&W. But the 44mag is the most punishing cartridge I care to shoot in an HG.