Some years ago there were supposedly kinetic energy weapons being developed. These would use tungsten rods dropped from orbit or from an ICBM that would hit their target at speeds of 17,000 mph and pack a near nuclear bomb punch. That would seem to be an ideal warhead for these new missiles.
Not only do you need the ability to launch that weight in the first place, if its in orbit it would require maneuvering engines and a tremendously high mass platform to effectively launch and accurately target from space
This stuff makes great science fiction but the physics are a real problem