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To: Wish2Post

Already posted here, in full, non clickbait version.

https://freerepublic.com/focus/f-news/4126665/posts

New York, N.Y., January 27, 2023 – Allegations have recently been made related to gain of function and directed evolution research at Pfizer and the company would like to set the record straight.

In the ongoing development of the Pfizer-BioNTech COVID-19 vaccine, Pfizer has not conducted gain of function or directed evolution research. Working with collaborators, we have conducted research where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern. This work is undertaken once a new variant of concern has been identified by public health authorities. This research provides a way for us to rapidly assess the ability of an existing vaccine to induce antibodies that neutralize a newly identified variant of concern. We then make this data available through peer reviewed scientific journals and use it as one of the steps to determine whether a vaccine update is required.

In addition, to meet U.S. and global regulatory requirements for our oral treatment, PAXLOVID™, Pfizer undertakes in vitro work (e.g., in a laboratory culture dish) to identify potential resistance mutations to nirmatrelvir, one of PAXLOVID’s two components. With a naturally evolving virus, it is important to routinely assess the activity of an antiviral. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus. In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus. It is important to note that these studies are required by U.S. and global regulators for all antiviral products and are carried out by many companies and academic institutions in the U.S. and around the world.

Fact-based information rooted in sound science is vitally important to overcoming the COVID-19 pandemic and Pfizer remains committed to transparency and helping alleviate the devastating burden of this disease.


4 posted on 01/28/2023 7:41:52 AM PST by Larry Lucido (Donate! Don't just post clickbait!)
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To: All

Pfizer has not conducted gain of function or directed evolution research and Bill Clinton did not have sex with that intern.


6 posted on 01/28/2023 7:54:16 AM PST by BipolarBob (The rumor has not been confirmed until the FBI officially denies it.)
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To: Larry Lucido

Quote
Fact-based information rooted in sound science is vitally important to overcoming the COVID-19 pandemic and Pfizer remains committed to transparency and helping alleviate the devastating burden of this disease.

Pandemic?

Scamdemic that has yet to be avenged..


9 posted on 01/28/2023 8:01:00 AM PST by delchiante
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To: Larry Lucido

Thanks for finding a prior posting. It is from another source, since Dr. Malone’s article had just been posted on his Substack about 30 minutes before I posted to FreeRepublic.

I did a search on the title but nothing came up, so I posted.

Dr Malone’s perspective, as opposed to Pfizer’s response, provides an explanation for what Pfizer is saying, AND HOW THE MAINSTREAM MEDIA HAS FALLEN INLINE WITH THEM. He also indicates that there is more coming on this matter. So stay tuned!


11 posted on 01/28/2023 8:09:29 AM PST by Wish2Post
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To: Larry Lucido
In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells.

Can someone explain to me how engineering a virus isn't the same as gain of function mutations?

Honest question, not being snarky.

19 posted on 01/28/2023 9:25:27 AM PST by usconservative (When The Ballot Box No Longer Counts, The Ammunition Box Does. (What's In Your Ammo Box?))
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To: Larry Lucido

“””Working with collaborators, we have conducted research”””


Naomi Wolf was on Bannon’s war room and quickly detailed the weasel words in Pfizer’s statement.

Who are the collaborators????????????????????


21 posted on 01/28/2023 9:53:56 AM PST by Presbyterian Reporter
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To: Larry Lucido

“Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus”

OH, That is re-assuring!

Based upon, Computer model analysis of mutations of a weaponized virus?


22 posted on 01/28/2023 10:08:38 AM PST by Texas Fossil ((Texas is not where you were born, but a Free State of Heart, Mind & Attitude!))
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