Splattered skunks do provide a difficult twist on this problem...
Yes, those were just some example calibers that I tried. I dont have a lot of handguns (yet) but the ones I have in other calibers are in classes that one would thing of as either derringer/deep concealment or full combat models. The little ones were too inaccurate and flung too tiny of a slug and the combat models generally threw too large of a slug and were a pain in the butt to have to carry while doing manual labor.
Thus, whats a good middle size frame with a good middleish range caliber?