Ooooof! I guess so... Call ya later...
The 44 special is a very effective manstopper at distances up to 50 yards in that particular barrel length. Get a longer tube on it, such as a smith and wesson sixgun with a six inch bbl, and you can reach out somewhat further.
I think I'd load it with Glaser Safety Slug or Powerball controlled expansion ammo in a short tube revolver like that. It will maximize your stopping power.
Don't forget, you cannot shoot the really hot loaded 44 specials in that Charter. It won't take the beating for very long.