We would've seen x42's symptoms during his nauseous 8 years in orifice; lesions on mucous membranes, fever, patchy loss of hair, rash... but just that horrible nose unless the comments by Monica are reliable. So i agree he is/was a magnet for contracting syphilis but methinks he instead probably has "just" pelvic inflammatory disease, herpes, condyloma, warts, and chlamydia.