Oh, good grief! No one "destroyed" Egypt and/or its skills and knowledge. It didn't ended like a brick through a plate glass window; it was more like the life cycle of some ancient tree.
No, it ended when the last Librarian of Alexandria was dragged from her chariot by a screaming mob of fanatics, had the flesh scraped from her bones by oyster shells, was then dismembered and, so it is said, her remains were partially eaten, and the rest burned.
Hypatia of Alexandria, 415 AD.