Nothing in the constitution relating to federal jurisdiction and enumerated powers has changed since then.
In addition, from the perspective of the presumption of liberty, the 9th amendment states:
The enumeration in the Constitution of certain rights, shall not be construed to deny or disparage others retained by the people."
Simply put, every citizen has the retained right to consume the chemical of their choice for the reason of their choice without federal intervention, nothwithstanding.
And any such intervention is unconstitutional for lack of jurisdiction, lack of enumerated power, and a violation of the 9th amendment, in the Bill of Rights.
Let me repeat: The Bill of Rights. Not the bill of privileges.
Well said, but always lost on "conservatives" who believe that being caged for years by government decree with sociopathic homosexual rapists is the appropriate fate for someone caught "possessing" a natural herb.