No doubt, since tiles ALWAYS fall off during re-entry... ALWAYS. It's considered NORMAL.
Finally, you posted a fact. Wow.
What's NORMAL this time? Was it just luck that there were 42 YEARS of flawless re-entry? This is not some big unknown. Approach the atmosphere at the correct angle and protect the vehicle from excessive heat. A former astronaut even said that re-entry is very peaceful and not violent like portrayed in the movies. The facts are on my side.