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SARS infects 'protected' medical staff Gloves, gowns, masks didn't stop outbreak at Sunnybrook
CanWest News Service - The Ottawa Citizen - canada.com ^ | April 20, 2003 | David Rider

Posted on 04/20/2003 6:43:29 AM PDT by CathyRyan

SARS has killed a 14th Canadian and infected a new cluster of Toronto hospital workers even though they were protected from head-to-toe in gowns, gloves, masks and eye shields.

The latest cluster has heightened concerns the mysterious Severe Acute Respiratory Syndrome virus can be spread via objects, in addition to face-to-face contact, and can remain potent on objects for much longer than previously believed.

Also, one expert predicted yesterday that SARS is likely to remain in Canada -- despite the current battle to contain it -- because people will continue to "import" it from lesser developed countries.

The latest Canadian death was a 99-year-old man who succumbed Friday, according to an Ontario government news release that provided no further details.

The previous 13 SARS deaths have all been in the Toronto area. Most have been elderly with underlying health problems, but experts are increasingly worried the virus is now making younger, otherwise healthy people critically ill.

The new cluster erupted at Sunnybrook and Women's College Health Sciences Centre in suburban Toronto, which has treated about half the region's SARS patients over the past month. It has 20 to 25 of them admitted at any given time.

As of yesterday, four staff members, including at least one doctor, a nurse and a respiratory therapist, were in hospital and almost certainly have SARS.

Another eight hospital staff members were sent into home quarantine as potential SARS cases.

A Vancouver hospital also isolated one of its wards yesterday when a nurse who worked there was identified as a possible SARS case.

Officials said they believe the Sunnybrook infections occurred during difficult intubations, including one last Sunday that took four hours. Intubation involves placing a tube down a patient's throat to facilitate breathing.

Both patients are now believed to be "super spreaders," or viral shedders, who are much more infectious than average SARS patients.

Some staff started feeling symptoms associated with SARS on Wednesday and Thursday. Senior hospital staff became aware of the threat late Thursday night.

Dr. Mary Vearncombe, the hospital's head of infection, prevention and control, said one worker's eye shield slipped during the Sunday intubation procedure, but there is no other known breach of the staff's "full-droplet" protection.

That includes gowns, gloves, eye shields and N-95 masks.

"We were using what both Health Canada and the (Atlanta-based) Centers for Disease Control consider to be maximal precautions for these patients," she said, adding it's possible some potentially infected staff was not present at the intubations.

That raises serious questions about how the virus was spread and whether the current precautions are enough to protect health care workers.

"We're examining everything we do and we're looking at a number of different options in terms of making that particular procedure safer for the health care workers," she said. One option is anesthetizing patients for intubation to reduce saliva spread.

Dr. Andrew Simor, the hospital's head of microbiology, said the virus continues to surprise the experts.

"We know that the (precautionary) measures that have been recommended should be adequate to deal with those (patients) but we're also impressed with just how easily the virus is spread, how it might contaminate the environment," he said.

Dr. Simor added that, in a Friday night conference call with Health Canada and the Centers for Disease Control and Prevention, a CDC expert surprised the others by revealing that the virus can remain potent on objects much longer than previously thought.

"What the CDC mentioned to us last night was that, in their studies, they found that you could still culture viable virus from surfaces after as much as 24 hours, which is longer than we normally expect viruses to be able to survive in the environment," he said.

In a statement yesterday, the World Health Organization said it is also concerned about the possibility of environmental transmission. It's looking closely at how SARS spread through a Hong Kong apartment complex, linked to the building's sewage system which carried the virus from an infected person.

However, the health body concluded there is "little risk" that environmental causes are behind a probable SARS case in a Toronto condominium which health officials have not been able to directly link to a SARS-infected family in the same building. The incubation period has passed with no further cases, the WHO noted.

The WHO is closely watching a disturbing trend in Hong Kong and Canada where SARS is striking younger, healthier people with greater ferocity. In particular, it is watching efforts to contain an outbreak among a 500-member, Toronto-area Catholic prayer group. Twenty-nine of them were infected, some of whom are not old or ill.

"The outbreak is regarded as a test case of whether rigorous contact tracing and other stringent public health measures can contain further spread even when very large numbers of persons may have been exposed," the WHO said.

Dr. Simor said he has seen the disturbing trend first-hand.

"The experience in Hong Kong has been a larger number of younger adults getting very severe illness, sometimes fatal," he said. "We are beginning to see that in Toronto as well."

The new cluster will further tax Toronto's almost-paralysed health care system. Instead of easing operating restrictions as it had planned, Sunnybrook has effectively closed its critical care, cardiovascular intensive care and SARS units for 10 days as a precaution.

"It's a huge burden on the system,'' said Leo Steven, the hospital's chief executive, adding that Sunnybrook, probably the biggest trauma centre in Canada, will now have to send trauma patients to other hospitals in Toronto, Hamilton and beyond.

Dr. Vearncombe predicted that even if containment measures are successful, Canada will have to learn to live with the SARS threat.

"I have some level of optimism that we can contain it in Toronto," she told reporters. "I have no optimism that we can contain it in developing areas of the world like mainland China so we will continue to import cases and we're going to have to remain absolutely vigilant."

Canada has about 300 probable and suspect cases of SARS in six provinces, mostly in Ontario.


TOPICS: News/Current Events
KEYWORDS: canada; incubationperiod; intubation; longevity; sars; toronto
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To: CathyRyan
Being a retired chip-maker and around 'clean rooms' most of my life, I have already wondered if placing these people in a clean room environment could be a partial solution.

Clean Rooms

I used to have an engineer who stayed in the clean-room as much as possible at certain times of the year...he had severe allergies (hay fever).

41 posted on 04/20/2003 8:57:23 AM PDT by blam
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To: aristeides
FYI on the mask issue. Click here for a story on how the n-95s are flying off the shelves.
42 posted on 04/20/2003 8:57:26 AM PDT by mewzilla
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To: Judith Anne
"But even so, that's an extremely contagious virus..."

When we find out that it can survive in the wild animal population, it's all over. (I wonder why we haven't heard about any animals being affected?)

43 posted on 04/20/2003 9:06:42 AM PDT by blam
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To: mewzilla
Yes, nebulized meds are given via a "pipe" apparatus or sometime via a mask with holes in it. Many respiratory meds given this way are designed to help liquefy secretions and stimulate coughing. Respiration is out into the general air of the room...even a reverse airflow isolation room is going to have some aerosolized droplets in it.

I didn't even think of this until you mentioned it...so far it's all theoretical to me, but dammit, it won't be this fall, imho.
44 posted on 04/20/2003 9:11:06 AM PDT by Judith Anne
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To: blam
(I wonder why we haven't heard about any animals being affected?)

It was successfully given to primates in tests.

Also, South China is a notorious hot house for all manner of viral infections due to the area's primitive intensive agriculture, placing humans, chickens, and pigs in close (and extremely filthy) proximity. Viruses spread back and forth inter-species, constantly mutating and with escalating virulence.

Because of this chronic public health hazard, South China is the source for most of the world's new strains of flu, colds, and other diseases.

The only exception is AIDS, which originated in Africans bush-meat eating of monkey brains, spread by gay flight attendents to the West and local "sex workers" to kill 1/5 of the Sub-Sahara heterosexual population.

45 posted on 04/20/2003 9:19:56 AM PDT by friendly
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To: Brian S
I doubt it's an engineered virus, but it certainly is a nasty one.

The slums of China are perfect natural habitats for trans-species bugs; that, combined with ChiCom incompetence has let this epidemic mushroom.

46 posted on 04/20/2003 9:24:14 AM PDT by Prince Charles
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To: friendly
"Because of this chronic public health hazard, South China is the source for most of the world's new strains of flu, colds, and other diseases."

I posted this bit of information on another thread last night.

"From Today's News: Independent (UK)"

"* A Dutch vet became the first human victim linked to the "bird flu" epidemic sweeping through Holland's poultry industry. The vet died of pneumonia after being infected by the virus which, although rarely transmitted to humans, killed six people in Hong Kong after emerging in 1997.""

I thought this virus had been contained after China killed millions of chickens.

47 posted on 04/20/2003 9:25:18 AM PDT by blam
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To: friendly
What PAL is really doing is fronting for trial attorneys awash in tobacco cash, and who are now seeking to bankrupt biotech and drug companies by suing for early termination of valid patents on a retainer basis

I suppose the bright side of all this (if there is a bright side) is these very same people trying to make a huge, fast buck have the identical potential of catching this and dying as the rest of us.

When (if) they start dying like flies, expect a sea-change in attitude. They'll be the ones screaming the loudest for an instant cure, no matter what the consequences.

One can only hope their deathbed conversions don't come too late for the rest of us.

48 posted on 04/20/2003 9:28:00 AM PDT by Gritty
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To: blam
The poultry farmers in the Delmarva peninsula of the US east coast are terrified of Bird Flu. Justifiably so, as it could wipe out an entire industry.
49 posted on 04/20/2003 9:29:30 AM PDT by friendly
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To: Gritty
One can only hope their deathbed conversions don't come too late for the rest of us.

Because they are sociopaths, lawyers don't make deathbed conversions.

50 posted on 04/20/2003 9:31:47 AM PDT by friendly
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To: mewzilla
HEPA air cleaners would help too I think.
51 posted on 04/20/2003 9:47:58 AM PDT by Justa
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To: blam
Pets dumped amid SARS uncertainty in Hong Kong

http://www.abc.net.au/news/newsitems/s836135.htm
52 posted on 04/20/2003 10:11:06 AM PDT by CathyRyan
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To: CathyRyan
""But we have told them that their is no evidence to suggest pets are involved in the transmission of SARS and we have urged them to keep their pets."

Thanks. So far, so good.

53 posted on 04/20/2003 10:16:15 AM PDT by blam
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To: CathyRyan
And now an article about Super-Spreaders.....

Are "Superspreaders" Ground Zero of SARS epidemic?

http://www.alertnet.org/thenews/newsdesk/N19261755.htm
54 posted on 04/20/2003 11:06:23 AM PDT by CathyRyan
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To: CathyRyan
...you could still culture viable virus from surfaces after as much as 24 hours...

At least this is longer than the normal shipping time for imports.

55 posted on 04/20/2003 11:15:45 AM PDT by forewarning
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To: CathyRyan
They went to Jupitor suits on March 31st in Singapore. Unfortunately on the 29th several staff were infected.

This virus must be easily airborne. Probably a very small virus too. Perhaps as they were removing the gowns, gloves and masks, it became airborne again from the surfaces of the protective gear. Also any exposed facial skin/hair not covered by the eye shields and mask might be problematic too. It sounds like a disinfectant decontamination shower is needed after any patient care.
56 posted on 04/20/2003 11:23:22 AM PDT by Domestic Church (AMDG...)
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To: not_apathetic_anymore
maybe there is some good news in that the graphs (while linear and upward) are at least not showing logarithmic increases.

On the other hand, this is steady growth despite increasing awareness and precautions.

57 posted on 04/20/2003 11:25:32 AM PDT by forewarning
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To: snopercod
I asked one of the medical Docs on FR if they were good for coronavirus and he said their trial runs were so bad, a complete joke, that they dropped the idea of selling them as prescriptive pharmaceuticals...so the over the counter approach is reflective of P.T. Barnum's perspective.

Some say it does work... who knows if you or I are in the small percentage of the trial run that had a positive result.
58 posted on 04/20/2003 11:31:56 AM PDT by Domestic Church (AMDG... but I have zicam in a kitchen cabinet along with a pound of garlic in the fridge)
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To: CathyRyan
"Officials said USAMRIID scientists "

Mmmm. This virus is going to change our lifestyles shortly. Supermarkets and other necessary shopping chains might want to change their business approach...drive through supermarkets...call ahead with your courtesy card info & pick up the groceries prepacked outside...or have delivery service.
59 posted on 04/20/2003 12:05:09 PM PDT by Domestic Church (AMDG... but I have zicam in a kitchen cabinet along with a pound of garlic in the fridge)
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To: Domestic Church; All
Interesting explanations of the super-spreaders in this article: City Of Fear, Hope: Hong Kong keeps a brave face as SARS crisis grows.
60 posted on 04/20/2003 12:06:18 PM PDT by aristeides
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