I agree that we should not amend the Constitution on a whim, but in this case I believe it is necessary to check the abuses of the judiciary - the Supreme Court could overrule anything short of a Constitutional amendment. Besides, there have been hundreds, if not thousands, of court decisions that "go against and try to modify the 10th Amendment." If we are going to change the Constitution, it should be done per the amendment process spelled out in Article V, not by judicial fiat.
As for the Second Amendment, the whim of activist judges is far more of a threat than the prospect of three-fourths of the states voting to repeal it. I seriously doubt a Constitutional amendment repealing it would have the broad support it would need.