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Cro Magnons in ice age times, and then the Bible antediluvians starting with Adam and Eve. The two groups are genetically identical or close enough to ignore any differences, but the cultures and technologies were so totally different as to prevent believing that the one group could be descended from the other.

Nonsense. The technological and artistic differences between Cro-Magnon and early Homo Sapien, and indeed, some current primitive cultures are so similar as to be indistinguishable. What's more, Cro-Magnoids still exist to this day in Easter island and their more archaic Palaeo-Atlantid versions in Sweden and Ireland.

There is a list of things which the Bible and Jewish literature would have to know about if you wanted to believe that Adam and Eve were descended From Cro Magnons and which the Bible and Midrashim appear to know nothing about:

Stone tools. Adam and Eve and their descendants were metal-tech people from day one. By contrast, human groups descended from Cro Magnons went on using stone tools until forced out of it by neighbors if they ever stopped at all. Aztecs were using stone knives and weapons when the Spanish arrived even though they used gold for ornaments and native Australians are killing kangaroos with such weapons now.
The atlatl i.e. the signature weapon of the Cro Magnon people. The Bible knows nothing of this weapon; the weapons of the Bible are the sword, the spear, the sling, and the bow. By contrast, amongst Cro Magnon descendants, the Aztecs were using atlatls agains the Spanish and native Australians use it to hunt kangaroos today.
Neanderthals and/or other hominids. The Bible knows nothing of hominids. By contrast, the Basque "Basajuan" appears to be a reflection of the Neanderthal and the Australian "Yowie" appears to be some sort of hominid.
An upper paleolithic world war in which all hominids were exterminated from the planet.
A "Purple Age", that is, a protracted age without any source of light such as we experience now, prior to the classical "Golden Age" of ancient literature. The Bible mentions the creation of light before the sun and moon are created and that the beginning is called an age when "the earth was without form, and void, and darkness was upon the face of the deep"; but Adam and Eve and the Bible antediluvians did not live on Earth in that age and the Bible beyond Genesis 1:2 does not speak of it again.

Likewise there is no version of anything which puts the metal ages prior to four or five thousand years ago which is ballpark for Adam and Eve and their descendants arriving on the scene.