But just for discussion, consider that one can look up "sex reassignment surgery" in their Biblical concordance and not find a thing. How does one argue Biblically against a series of surgical operations intended to be a therapeutic approach to a disorder now known as "Gender Dysphoria" for which the "cure" is supposedly transsexual conversion?
I would approach it as, well, God made man and God made woman, and He was pleased with His creation the way it was. God didn't mess up, change His mind, and take either one back to swap parts around like you would a Mr. Potato Head.
There was a bumper sticker around several years ago that said "God doesn't make mistakes" -- and it seems to me that Genesis is pretty clear about this.
Just my $.02 - YMMV.
God created you as you are. He did not trap Adam in a woman's body or vice versa. He made them in the body of the gender HE wants you to be.
Further, if you are a woman and mutilate yourself - are you attracted to men? Then you are obviously biologically a woman still.........or you are willingly attempting to become a gay "man." - and directly thumbing your nose at God
Thou shalt not lie with mankind, as with womankind: it is abomination. Leviticus 18:22
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And he answered and said unto them, Have ye not read, that he which made them at the beginning made them male and female,
And said, For this cause shall a man leave father and mother, and shall cleave to his wife: and they twain shall be one flesh?
Wherefore they are no more twain, but one flesh. What therefore God hath joined together, let not man put asunder.
They say unto him, Why did Moses then command to give a writing of divorcement, and to put her away?
He saith unto them, Moses because of the hardness of your hearts suffered you to put away your wives: but from the beginning it was not so. Matthew 19:4-8
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Therefore God gave them up in the lusts of their hearts to impurity, to the dishonoring of their bodies among themselves, because they exchanged the truth about God for a lie and worshiped and served the creature rather than the Creator, who is blessed forever! Amen.
For this reason God gave them up to dishonorable passions. For their women exchanged natural relations for those that are contrary to nature; and the men likewise gave up natural relations with women and were consumed with passion for one another, men committing shameless acts with men and receiving in themselves the due penalty for their error.
And since they did not see fit to acknowledge God, God gave them up to a debased mind to do what ought not to be done. They were filled with all manner of unrighteousness, evil, covetousness, malice. They are full of envy, murder, strife, deceit, maliciousness. They are gossips, slanderers, haters of God, insolent, haughty, boastful, inventors of evil, disobedient to parents, foolish, faithless, heartless, ruthless.
Though they know God's righteous decree that those who practice such things deserve to die, they not only do them but give approval to those who practice them.Romans 1:24-32
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Know ye not that the unrighteous shall not inherit the kingdom of God? Be not deceived: neither fornicators, nor idolaters, nor adulterers, nor effeminate, nor abusers of themselves with mankind,
Nor thieves, nor covetous, nor drunkards, nor revilers, nor extortioners, shall inherit the kingdom of God.
And such were some of you: but ye are washed, but ye are sanctified, but ye are justified in the name of the Lord Jesus, and by the Spirit of our God. I Corinthians 6:9-11