I tend to follow St. Thomas Aquinas: drink until you feel dizzy, anything past that is drunkenness and a sin :-)
My dad always said to drink standing up. . .because when you fall down you know you’ve had enough. ;-)
But what if Aquinas could once drink just x amount and get dizzy and years down the road it took twice as much to get dizzy?
When then is the limit that must never be passed if tolerance can be increased?