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Are you confusing the words “brothers” or “sisters” with the word in use at that time: “brethren”, which was used for all relatives?

They were extended family or friends.

It certainly was not and they are not...

Brothers

ἀδελφός
adelphos
ad-el-fos'
From G1 (as a connective particle) and δελφύς delphus (the womb); a brother (literally or figuratively) near or remote (much like [H1]): - brother.

Adelphos means a male blood relative from the same, immediate family...Either literally or figuratively...

Many minister use the phrase “Brothers and sisters”, but they are really talking to their congregation.

Do you have any idea why??? No??? It's because we have all been born again...From Above...From the same father...We are blood brothers spiritually and figuratively...

And sisters???

ἀδελφή
adelphē
ad-el-fay'
Feminine of G80; a sister (natural or ecclesiastical): - sister.

This makes it so simple you couldn't miss it with the Hubble telescope...

Adelphe is a natural (real blood) sister or an ecclesiastical, born again sister, born from God, the same as 'brothers'...

Those words have never meant cousin, nephew, kin, aunt, uncle or kinsmen...

And since these words are used to describe Jesus' immediate family, we know that Jesus had brothers and sisters...And the only way they could be natural brothers and sisters is if they all had the same father, or mother...