She just needs to increase her antibiotic load.
She may have reached a point where she is on so many drugs, that they are starting to counteract each other. That was the beginning of the end of my father...the doctors couldn’t figure out which meds to give him, or how much, because of the very complicated interactions between the drugs. They very quickly reached the decision that they couldn’t do anything else, as too much was going wrong. Pain control was the only strategy left.