No. But it sure can gum up the works, and slow things down. And we are running out of time - we don't need to be in the position of having the clock run out on us on some petty BS like this.
If it isn't this, it will be something else. It's simply what they do.
After all, this isn't the first resignation they've demanded. They've gone after Delay, Rumsfeld, Ashcroft, Ridge. They've gone after everyone. And they've made an issue of everything. And guess what? None of it has worked.
This latest frothing lather is merely one of many. If it wasn't Rove, it would be someone else.