All of the V-6 engines currently used by Ford in their passenger cars (3.0/3.5/4.0) are 60 degree designs. The Audi V-6, which draws rave reviews, happens to have a 90 degree layout.
Part of the problem is that they really were V8’s with two cylinders lopped off. Without the additional engineering needed to make a 90 degree V6 work properly, they didn’t do well.