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One's chromosomes determine anatomy. Your anatomy does not determine who you are.

One's anatomy plays a huge role in how the world see's that person and how that person is required to interact with the world, but one's anatomy and chromosomes do not determine who they are.

Is it simply breasts and a vagina that make a woman significantly different in personality than a man?

Why do women like the things they like and do the things they do? Is it because they have a vagina? Obviously not.

There is something innately different about women. I don't mean anatomically or physiologically. I mean with how they interact in the world.

Babies are born with defects all day long. Some of those defects are very visible.

Why is it impossible to understand or believe that a baby could be born male, but innately they are female? It's no fault of their's.

Freddie Mercury drag queens and cross-dressers are offensive to me, and I believe they do so to shock, or excite certain segments of society. I think they do a gross disservice to those people that were born into bodies and lives that they did not feel at home in. Their personalities did not match who they were on the inside and they simply wished to live life, and express themselves in a manner that was more comfortable with who they really are.

Would you consider a baby born with some visible physical defect, a freak? Why then someone that is born into a body that does not reflect their personality and interests?

“One’s chromosomes determine anatomy.”
—Agreed.

“Your anatomy does not determine who you are.”
—Sorry, I don’t buy that secular humanist pap.

“One’s anatomy plays a huge role in how the world see’s that person and how that person is required to interact with the world, but one’s anatomy and chromosomes do not determine who they are.”
—Anatomy is the physical reality of a man or woman’s identity. It’s not to be confused with free will. If a man wants to think he’s a woman, he can choose to do that, but it doesn’t negate the physical reality of his XY chromosome. He is living in a delusion.

“Is it simply breasts and a vagina that make a woman significantly different in personality than a man?”
—Along with the physical reality of anatomy, there is also the mental and spiritual realm.

“Why do women like the things they like and do the things they do? Is it because they have a vagina? Obviously not.”
—Having a vagina is only part of it. Don’t forget about the mental and spiritual parts of a whole person.

“There is something innately different about women. I don’t mean anatomically or physiologically. I mean with how they interact in the world.”
—Innately means they were born with an XX chromasome. And yes, I agree women are innately different than men.

“Babies are born with defects all day long. Some of those defects are very visible.”
—Agree. But most transsexuals don’t have this issue. They are either clearly XX or XY. The deviation most likely is mental or spiritual.

“Why is it impossible to understand or believe that a baby could be born male, but innately they are female? It’s no fault of their’s.”
—Because innately a person is born either XX or XY, unless there is a genetic defect of the hermaphrodite. The case there is very rare.

“Freddie Mercury drag queens and cross-dressers are offensive to me, and I believe they do so to shock, or excite certain segments of society. I think they do a gross disservice to those people that were born into bodies and lives that they did not feel at home in.”
—I don’t think Freddie Mercury was an actual transsexual. He didn’t have the surgery, did he? I though he was only a theatrical homosexual. Are you mixing up cross-dressers with transsexuals?

“Their personalities did not match who they were on the inside and they simply wished to live life, and express themselves in a manner that was more comfortable with who they really are.”
—This is a mental/spiritual issue, which has nothing to do with genetics.

“Would you consider a baby born with some visible physical defect, a freak?”
—Not so much a ‘freak,’ but an anomaly. Having a mix-up concerning XX and XY is not normal. But most transsexuals don’t have this problem.

“Why then someone that is born into a body that does not reflect their personality and interests?”
—For the majority of transsexuals, the problem is mental and spiritual. People have the free will to choose their interests, and the personality is also a reflection of mental state. Just because a man wishes he could be a woman doesn’t make is so, even after surgery. The reality of anatomy cannot be denied.

The woman who had surgery to “make her a man” recently had a baby. She may think she’s a man, and media and society may call her a man, but she had a baby. She’s a woman—a very confused woman. That can’t be denied.

“One’s chromosomes determine anatomy. Your anatomy does not determine who you are.”

It can even be more complicated. Example: Women, who have androgen insensitivity syndrome. They have breasts and a vagina, but they are actually XY. Why? There is a gene on the X chromosome called AR, the androgen receptor. In their case, the gene is an anomaly, and will not allow the transport of androgen across the cell membrane. They do identify as women.

Yet, another example: Women with complet gonadal agenesis, who are XY, and have a vagina, uterus, and fallopian tubes, but no gonads. They fail to develop breasts, and require hormone therapy to physically mature. They also develop a female gender identity.

Then, let’s examine the case of girls with congenital adrenal hyperplasia. There is a genetic anomaly, that blocks the production of cortisol. The result is high levels of androgens in the fetal blood stream. Typically, these individuals exhibit various degrees of physical masculinization (fusing of the labia, enlargement of the clitoris, etc.) Behaviorally, they are referred to as tomboys, and some research has indicated about 40% of them are lesbian. In extreme cases, the labia will completely fuse, and the clitoris will become a phallus. The child will most probably identify as a boy, even though they are XX.