The new government was to be strong ONLY as compared to the old one under the Articles of Confederation. It was still meant to be wan, pale and anemic as compared to We, the People, its sole source of legitimate authority. But you are one who LIKES a robust FedGov when it comes to YOUR pet schemes for controlling others, if I recall correctly, and I believe I do!
The federal government was designed to be weak with regard to domestic affairs only to protect the powers of each separate state from federal interference. Laws against dangerous drugs, gambling and prostitution are and should be enforced by the states, unless they are matter of national security. Illegal trafficking of drugs and prostitutes into the country are issues of national security.