Todd Akin & Tommy Thompson are having trouble and neither were tea party candidates - in Akin's race tea party support split 3 ways, and Thompson is establishment all the way and only a big push by DeMint & Club for Growth stopped the tea party candidate from winning that primary. Rick Berg has had some difficulty in NoDak and he's establishment all the way.
Mourdock should be fine. Milbank cites Dick Lugar's undercutting of Mourdock as if that's the tea party hurting GOP electoral chances, which is unusually obtuse even for the MSM.
2010 was a wreck, though, with more electable conservatives rejected in Nevada and Colorado, costing us two seats. Blame the Tea Party Express group for the Nevada disaster at least. Ken Buck's loss was more due to a hatchet job by the media, but Jane Norton would've won. (I don't care about Mike Castle's loss.)