Opium, cocaine, and marijuana have been used since time immemorial. The active ingredient for cocaine was first isolated and morphine and heroin were invented in the 19 th century. Amphetamines and barbiturates, were developed in that century as well. PCP, LSD, and certain other substances didn’t come along until shortly before the Drug War, so I guess you’re on solid ground there. Otherwise, you are remarkably ignorant.
And the organic predecedent of LSD is a form of ergot-corn smut. LSD was first experimented with by the government, supposedly looking for a cure for serious and recurrent psychosis-boy, did they ever get that wrong...
Morphine was not invented it was isolated.