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Posted on 04/05/2013 11:13:05 AM PDT by Jim Robinson
Howdy everyone!!
Woo hoo!! Our 2nd quarter FReepathon is well underway!!
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In a finished basement with a bar and pool table circa 1950’s. :-D
Too late, Doctor.
Thanks anyway. Immediate relief is on the way!
:)
**************************
Yes? Please be careful to be very strict with dosage guidelines and don't have anything alcoholic, onyx.
From Wikipedia:
Paracetamol hepatotoxicity is, by far, the most common cause of acute liver failure in both the United States and the United Kingdom.[10][42] Toxicity of paracetamol arises often due to its quinone metabolite.[43] Paracetamol overdose results in more calls to poison control centers in the US than overdose of any other pharmacological substance.[44] Signs and symptoms of paracetamol toxicity may initially be absent or vague. Untreated overdose can lead to liver failure and death within days. Treatment is aimed at removing the paracetamol from the body and replacing glutathione.[43] Activated charcoal can be used to decrease absorption of paracetamol if the patient presents for treatment soon after the overdose. While the antidote, acetylcysteine, (also called N-acetylcysteine or NAC) acts as a precursor for glutathione, helping the body regenerate enough to prevent damage to the liver, a liver transplant is often required if damage to the liver becomes severe.[7] N-Acetylcysteine also helps in neutralizing the imidoquinone metabolite of acetaminophen.[43] Renal failure is also a possible side effect.
There are tablets available (brand-name in the UK Paradote) that combine paracetamol with an antidote (methionine), to protect the liver in case of an overdose.
In June 2009, a U.S. Food and Drug Administration (FDA) advisory committee recommended that new restrictions should be placed on paracetamol usage in the United States to help protect people from the potential toxic effects. The maximum dosage at any given time would be decreased from 1000 mg to 650 mg, while combinations of paracetamol and narcotic analgesics would be prohibited. Committee members were particularly concerned by the fact that the present maximum dosages of paracetamol had been shown to produce alterations in hepatic function.[45] On January 13, 2011, the FDA asked manufacturers of prescription combination products containing paracetamol to limit the amount of paracetamol to no more than 325 mg per tablet or capsule and began requiring manufacturers to update the labels of all prescription combination paracetamol products to warn of the potential risk for severe liver damage.[46][47][48][49] Manufacturers will have three years to limit the amount of paracetamol in their prescription drug products to 325 mg per dosage unit.[47][49] In November 2011, the Medicines and Healthcare products Regulatory Agency revised UK dosing of liquid paracetamol for children.[50] [edit]
What can’t you take besides aspirin? Tylenol? Ibuprofen?
I really don’t recall what he said or the reasons. I just remember aspirin and 30 days. I’d ask DrO, but he went upstairs for his nap. I know aspirin is a blood thinner. I’m not going to give it another thought.
Thank you, Mommy Dearest...LOL.
:)
Okay. You’re a big girl and ain’t no dummy. :-)
:) LOL!
That reminds me, how’s YOUR back today?
LOL. Well, at least that one pill worked!!!
You have a great doctor. :)
Not as bad as yesterday. Yesterday my back hurt when I got up and I aggravated it. I know better! lol
:)
Little Socks cat spent last night throwing up. He wretched so hard that he woke me up. Then he slept for hours. He seems to be okay now.
Yeah, and you and DJ are my back-up’s!
LOL.
Yes. :)
Was that from eating the frog?
What’s for dinner tonight?
I barely made it home from the restaurant!
I have to X another item from my list of foods.....LOL.
“Cream Sauce.” (I forgot about the butter in it... I ordered “creamed spinach”).
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