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Down syndrome reversed in newborn mice with single injection
ABC ^ | 9/5/2013 | Staff

Posted on 09/05/2013 9:54:28 AM PDT by Titus-Maximus

US researchers have found a way to reverse Down syndrome in newborn lab mice by injecting an experimental compound that causes the brain to grow normally.

The study, published in the Science Translational Medicine journal, offers no direct link to a treatment for humans but scientists are hopeful it may offer a path towards future breakthroughs.

There is no cure for Down syndrome, which is caused by the presence of an additional chromosome and results in intellectual disabilities, distinctive facial features and other health problems.

The team at Johns Hopkins University of Medicine, in Baltimore, used lab mice that were genetically engineered to have extra copies of about half the genes found on human chromosome 21, leading to Down syndrome-like conditions such as smaller brains and difficulty learning to navigate a maze.

On the day the mice were born, scientists injected them with a small molecule known as a sonic hedgehog pathway agonist.

(Excerpt) Read more at abc.net.au ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: downsyndrome; prolife
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Injections helped both memory and learning, they are rushing inoculations to the White House, if it works with mice, it should work with rats....
1 posted on 09/05/2013 9:54:28 AM PDT by Titus-Maximus
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To: Titus-Maximus
To those unfamiliar with the world of medical research,anything that comes out of Harvard,Hopkins,Mayo Clinic and a few others is *absolutely* listened to by the wider medical world.
2 posted on 09/05/2013 9:58:15 AM PDT by Gay State Conservative (If Obama Had A City It Would Look Like Detroit)
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To: Titus-Maximus
Didn't I see this in a movie forty years ago?


3 posted on 09/05/2013 9:58:27 AM PDT by billorites (freepo ergo sum)
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To: Titus-Maximus

“if it works with mice, it should work with rats....”

LOL


4 posted on 09/05/2013 9:58:55 AM PDT by Not gonna take it anymore (If Obama were twice as smart as he is, he would be a wit)
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To: Titus-Maximus
scientists injected them with a small molecule known as a sonic hedgehog pathway agonist.

Oh, great. Now Sega will want compensation for trademark infringement.
5 posted on 09/05/2013 9:59:35 AM PDT by Dr. Sivana (There's no salvation in politics.)
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To: Titus-Maximus

Hmmmm, White House lab Rats ... I’m undecided on this one.


6 posted on 09/05/2013 10:00:20 AM PDT by shove_it (long ago Orwell and Rand warned us of 0bama's America)
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To: Titus-Maximus

LMFAO


7 posted on 09/05/2013 10:01:15 AM PDT by Rannug ("God has given it to me, let him who touches it beware.")
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To: Titus-Maximus

“reversed” ?

Up syndrome?

Ok..shouldn’t joke on this.

It would be wonderful to see this come to fruition!

Pro-Aborts will be sorry to see an end to the abortion of 90% of those diagnosed, pre-natal.

Obamacare will find a way to stall any progress in this area.


8 posted on 09/05/2013 10:03:38 AM PDT by G Larry (Let his days be few; and let another take his office. Psalms 109:8)
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To: billorites

Nice catch! I saw that movie in school and it was very memorable! ‘Flowers for Algernon’


9 posted on 09/05/2013 10:04:02 AM PDT by MeganC (A gun is like a parachute. If you need one, and don't have one, you'll never need one again.)
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To: shove_it

I dimly remember a cartoon about mice in the White House...


10 posted on 09/05/2013 10:07:12 AM PDT by GeronL
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To: Titus-Maximus
Oh how wonderful..I still say these are little angels sent to us to remind us no matter what always keep a smile..those precious little angels I love so much..I don't have a downs child but my daughter worked for MHMR and she was a teacher for these bright little children..They give out lots of hugs..
11 posted on 09/05/2013 10:13:09 AM PDT by PLD
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To: Titus-Maximus

I predict that some parents of kids with Down’s syndrome will protest a potential cure.


12 posted on 09/05/2013 10:13:54 AM PDT by dangerdoc (see post #6)
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To: Titus-Maximus

LOL - I nominate you for the post of the day!!!


13 posted on 09/05/2013 10:15:54 AM PDT by taxcontrol
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To: dangerdoc

Likely. Some people find perverse pleasure in having family member with some defect. It becomes a social identity for them.


14 posted on 09/05/2013 10:17:53 AM PDT by Myrddin
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To: billorites

my exact thought.


15 posted on 09/05/2013 10:20:00 AM PDT by mountn man (The Pleasure You Get From Life Is Equal To The Attitude You Put Into It)
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To: Titus-Maximus

Please do not insult rats in that manner. They are lawyers, period.

Old joke! Many research labs have discontinued using rats for experiments and have begun using lawyers instead. When asked why the researchers replied that:
1. There are more lawyers than rats;
2. employees do not get nearly as attached to lawyers as they sometimes do with rats, and
3. there are just somethings that rats just wont do.


16 posted on 09/05/2013 10:20:27 AM PDT by dirtymac (1)
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To: Myrddin

17 posted on 09/05/2013 10:22:26 AM PDT by mountn man (The Pleasure You Get From Life Is Equal To The Attitude You Put Into It)
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To: MeganC

See to me that the name of the movie was the name of the “slow” character, who became brilliant.


18 posted on 09/05/2013 10:27:30 AM PDT by wizr (We are "one Nation, under God " or "one nation, trod under ". Keep the Faith.)
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To: Myrddin
“Likely. Some people find perverse pleasure in having family member with some defect. It becomes a social identity for them.”

Absolutely. My stepson is a dwarf and he and my wife dropped out of several support groups because of the victim mentality. She raised him to overcome, not look for special treatment.

19 posted on 09/05/2013 10:27:31 AM PDT by CrazyIvan (Obama phones= Bread and circuits.)
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To: MeganC

Seems to me that the name of the movie was the name of the “slow” character, who became brilliant.


20 posted on 09/05/2013 10:28:39 AM PDT by wizr (We are "one Nation, under God " or "one nation, trod under ". Keep the Faith.)
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