You are minimizing the difference between a "law" and a Constitutional Amendment.
So you agree that a Constitutional amendment would be required to re-ban alcohol? Do you agree that a Constitutional amendment is required to give the federal government legitimate authority to ban drugs other than alcohol? (My answers are yes and yes.)
No. Drugs are an existential threat to the existence of government and are therefore expressly covered under the defense clause of the US Constitution.
It is no different in effect than that of someone importing biological weapons to use against us. Actually biological weapons are probably not as deadly to our system of governance as are drugs.
China legalized drugs. Drugs Destroyed the nation of China. Legalized drugs are an existential threat to any government which tolerates them.