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Scientists find key to 'turbo-charging' immune system to kill all cancers
www.telegraph.co.uk ^ | 7:00PM BST 16 Apr 2015 | By Sarah Knapton, Science Editor

Posted on 04/17/2015 8:11:03 AM PDT by Red Badger

A protein which ‘turbo-charges’ the immune system so that it can fight off any cancer or virus has been discovered by scientists.

In a breakthrough described as a ‘game-changer’ for cancer treatment, researchers at Imperial College found a previously unknown molecule which boosts the body’s ability to fight off chronic illnesses.

Scientists at Imperial College London, who led the study, are now developing a gene therapy based on the protein and hope to begin human trials in three years.

“This is exciting because we have found a completely different way to use the immune system to fight cancer,” said Professor Philip Ashton-Rickardt, from the Section of Immunobiology in the Department of Medicine at Imperial, who led the study.

“It could be a game-changer for treating a number of different cancers and viruses.

“This is a completely unknown protein. Nobody had ever seen it before or was even aware that it existed. It looks and acts like no other protein.”

The protein – named lymphocyte expansion molecule, or LEM, promotes the spread of cancer killing ‘T cells’ by generating large amounts of energy.

Normally when the immune system detects cancer it goes into overdrive trying to fight the disease, flooding the body with T cells. But it quickly runs out of steam.

However the new protein causes a massive energy boost which makes T cells in such great numbers that the cancer cannot fight them off.

It also causes a boost of immune memory cells which are able to recognise tumours and viruses they have encountered previously so there is less chance that they will return.

The team made the discovery while screening mice with genetic mutations. They found one type produced ten times the number of cancer-fighting T cells, suppressing infections and becoming resistant to cancer.

(Excerpt) Read more at telegraph.co.uk ...


TOPICS: Business/Economy; Culture/Society; Technical; United Kingdom
KEYWORDS: cancer; chemo; health; medicine
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1 posted on 04/17/2015 8:11:03 AM PDT by Red Badger
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To: Red Badger

Gotta be a catch — too easy.


2 posted on 04/17/2015 8:12:12 AM PDT by George from New England (escaped CT in 2006, now living north of Tampa)
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To: George from New England
However the new protein causes a massive energy boost which makes T cells in such great numbers that the cancer cannot fight them off. It also causes a boost of immune memory cells which are able to recognise tumours and viruses they have encountered previously so there is less chance that they will return.

Sounds really great....................

3 posted on 04/17/2015 8:13:30 AM PDT by Red Badger (Man builds a ship in a bottle. God builds a universe in the palm of His hand.............)
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To: Red Badger

Before I continue reading... let me guess...

It works in the lab or on mice... nothing beyond that.


4 posted on 04/17/2015 8:14:52 AM PDT by SeekAndFind
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To: Red Badger

One can only hope.


5 posted on 04/17/2015 8:15:35 AM PDT by Chainmail (A simple rule of life: if you can be blamed, you're responsible.)
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To: George from New England

You have to take a vaccine that has a GPS tracking device and citizen identification module that will be necessay to buy and sell goods later. The MOTB666 vaccine. Available everywhere for free as a courtesy by the U.S. FedGov.


6 posted on 04/17/2015 8:15:55 AM PDT by jsanders2001
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To: Red Badger

They will ‘allow’ cancer cures as soon as they can get a comparable cash cow disease in the pipeline.


7 posted on 04/17/2015 8:16:29 AM PDT by maine-iac7 ( million ii)
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To: George from New England

yeah, probably massive risk of auto-immune diseases like MS.


8 posted on 04/17/2015 8:16:43 AM PDT by Scutter
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To: Red Badger

9 posted on 04/17/2015 8:18:42 AM PDT by 2ndDivisionVet (You can help: https://donate.tedcruz.org/c/FBTX0095/)
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To: Scutter
probably massive risk of auto-immune diseases

There are no silver bullets, the body is tuned to maintain health and doesn't do well under stress like a fired-up immune system.

10 posted on 04/17/2015 8:24:26 AM PDT by palmer (Net "neutrality" = Obama turning the internet into FlixNet)
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To: Red Badger

It is not Dr. Kripin I hope...


11 posted on 04/17/2015 8:25:07 AM PDT by Resolute Conservative
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To: 2ndDivisionVet

use D3 -

or find the ‘sun window’ for YOUR back yard...

http://aa.usno.navy.mil/data/docs/AltAz.php


12 posted on 04/17/2015 8:32:04 AM PDT by maine-iac7 ( million ii)
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To: maine-iac7

“This page can’t be displayed”


13 posted on 04/17/2015 8:36:33 AM PDT by 2ndDivisionVet (You can help: https://donate.tedcruz.org/c/FBTX0095/)
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To: George from New England

There are a large number of cancer cases where the human body just fights off “incurable” cancer.

I’ve been told that harnessing this ability is the ultimate goal of cancer research.


14 posted on 04/17/2015 8:41:54 AM PDT by Jewbacca (The residents of Iroquois territory may not determine whether Jews may live in Jerusalem)
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To: George from New England

Not at all.

It’s estimated it will take about ten years to go into mass production.

When it does, scientists predict, it does it will make electricity too cheap to meter, and finally end our reliance on risky foreign oil.

Oops, sorry. Wrong miracle invention.


15 posted on 04/17/2015 8:43:30 AM PDT by Flash Bazbeaux
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To: Scutter

>>> probably massive risk of auto-immune diseases like MS. <<<

“Yes, you are in complete remission. That’s the good news. The bad news is you have . . .

Acute Disseminated Encephalomyelitis (ADEM)
Acute necrotizing hemorrhagic leukoencephalitis
Addison’s disease
Agammaglobulinemia
Alopecia areata
Amyloidosis
Ankylosing spondylitis
Anti-GBM/Anti-TBM nephritis
Antiphospholipid syndrome (APS)
Autoimmune angioedema
Autoimmune aplastic anemia
Autoimmune dysautonomia
Autoimmune hepatitis
Autoimmune hyperlipidemia
Autoimmune immunodeficiency
Autoimmune inner ear disease (AIED)
Autoimmune myocarditis
Autoimmune oophoritis
Autoimmune pancreatitis
Autoimmune retinopathy
Autoimmune thrombocytopenic purpura (ATP)
Autoimmune thyroid disease
Autoimmune urticaria
Axonal & neuronal neuropathies
Balo disease
Behcet’s disease
Bullous pemphigoid
Cardiomyopathy
Castleman disease
Celiac disease
Chagas disease
Chronic fatigue syndrome**
Chronic inflammatory demyelinating polyneuropathy (CIDP)
Chronic recurrent multifocal ostomyelitis (CRMO)
Churg-Strauss syndrome
Cicatricial pemphigoid/benign mucosal pemphigoid
Crohn’s disease
Cogans syndrome
Cold agglutinin disease
Congenital heart block
Coxsackie myocarditis
CREST disease
Essential mixed cryoglobulinemia
Demyelinating neuropathies
Dermatitis herpetiformis
Dermatomyositis
Devic’s disease (neuromyelitis optica)
Discoid lupus
Dressler’s syndrome
Endometriosis
Eosinophilic esophagitis
Eosinophilic fasciitis
Erythema nodosum
Experimental allergic encephalomyelitis
Evans syndrome
Fibromyalgia**
Fibrosing alveolitis
Giant cell arteritis (temporal arteritis)
Giant cell myocarditis
Glomerulonephritis
Goodpasture’s syndrome
Granulomatosis with Polyangiitis (GPA) (formerly called Wegener’s Granulomatosis)
Graves’ disease
Guillain-Barre syndrome
Hashimoto’s encephalitis
Hashimoto’s thyroiditis
Hemolytic anemia
Henoch-Schonlein purpura
Herpes gestationis
Hypogammaglobulinemia
Idiopathic thrombocytopenic purpura (ITP)
IgA nephropathy
IgG4-related sclerosing disease
Immunoregulatory lipoproteins
Inclusion body myositis
Interstitial cystitis
Juvenile arthritis
Juvenile diabetes (Type 1 diabetes)
Juvenile myositis
Kawasaki syndrome
Lambert-Eaton syndrome
Leukocytoclastic vasculitis
Lichen planus
Lichen sclerosus
Ligneous conjunctivitis
Linear IgA disease (LAD)
Lupus (SLE)
Lyme disease, chronic
Meniere’s disease
Microscopic polyangiitis
Mixed connective tissue disease (MCTD)
Mooren’s ulcer
Mucha-Habermann disease
Multiple sclerosis
Myasthenia gravis
Myositis
Narcolepsy
Neuromyelitis optica (Devic’s)
Neutropenia
Ocular cicatricial pemphigoid
Optic neuritis
Palindromic rheumatism
PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus)
Paraneoplastic cerebellar degeneration
Paroxysmal nocturnal hemoglobinuria (PNH)
Parry Romberg syndrome
Parsonnage-Turner syndrome
Pars planitis (peripheral uveitis)
Pemphigus
Peripheral neuropathy
Perivenous encephalomyelitis
Pernicious anemia
POEMS syndrome
Polyarteritis nodosa
Type I, II, & III autoimmune polyglandular syndromes
Polymyalgia rheumatica
Polymyositis
Postmyocardial infarction syndrome
Postpericardiotomy syndrome
Progesterone dermatitis
Primary biliary cirrhosis
Primary sclerosing cholangitis
Psoriasis
Psoriatic arthritis
Idiopathic pulmonary fibrosis
Pyoderma gangrenosum
Pure red cell aplasia
Raynauds phenomenon
Reactive Arthritis
Reflex sympathetic dystrophy
Reiter’s syndrome
Relapsing polychondritis
Restless legs syndrome
Retroperitoneal fibrosis
Rheumatic fever
Rheumatoid arthritis
Sarcoidosis
Schmidt syndrome
Scleritis
Scleroderma
Sjogren’s syndrome
Sperm & testicular autoimmunity
Stiff person syndrome
Subacute bacterial endocarditis (SBE)
Susac’s syndrome
Sympathetic ophthalmia
Takayasu’s arteritis
Temporal arteritis/Giant cell arteritis
Thrombocytopenic purpura (TTP)
Tolosa-Hunt syndrome
Transverse myelitis
Type 1 diabetes
Ulcerative colitis
Undifferentiated connective tissue disease (UCTD)
Uveitis
Vasculitis
Vesiculobullous dermatosis
Vitiligo
Wegener’s granulomatosis (GPA)”


16 posted on 04/17/2015 8:43:32 AM PDT by Jeff Chandler (Doctrine doesn't change. The trick is to find a way around it.)
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To: Red Badger

[[Scientists find key to ‘turbo-charging’ immune system to kill all cancers]]

I guess people with overactive immune systems which attack their bodies/healthy tissue are out of luck then


17 posted on 04/17/2015 8:47:49 AM PDT by Bob434
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To: Red Badger

Does it work for Marxist and Islamist,too?


18 posted on 04/17/2015 8:48:48 AM PDT by Leep (To put it in laymen's terms liberal/progressive ist coo coo.)
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To: Red Badger

what about the possibility of increased risk of psoriasis, atopic dermatitis, and mycosis fungoides


19 posted on 04/17/2015 8:51:10 AM PDT by mjp ((pro-{God, reality, reason, egoism, individualism, natural rights, limited government, capitalism}))
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To: 2ndDivisionVet

link works on my ‘puter fine - It’s from The United States Naval Observatory (USNO)

http://aa.usno.navy.mil/data/docs/AltAz.php


20 posted on 04/17/2015 8:51:58 AM PDT by maine-iac7 ( million ii)
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