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Considering that the whole place is covered with chunks of sulfur, one just might think it was some kind of volcanic event. There is no radiation present in the region.
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Last time I spoke with Dr. Collins he said the jury was still out on a nuclear type explosion...
http://www.newscientificevidenceforgod.com/2012/04/was-sodom-and-gomorrah-wiped-out-by.html
I’ve read where some think the evidence points to a comet hitting (above link), or another where a meteor grazed the top of the alps. Such an event would cover a large zone of effect (not just a city), and could/would account for similar findings in nearby areas.
The above link mentions the Bible verses, and says Lot saw destruction of “all the land of the plain”.