Not in my work and study. My background is test engineering, and I found that some people of a particular genetic pre-disposition, Aspartame DOES very much affect blood sugar. The blood sugar goes up dramatically and STAYS UP no matter how much one exercises or takes insulin. It takes days for these poor people to purge the Aspartame from their system. Now, if they had raw honey - blood sugar would spike, but would ultimately go down, because there is enough PURE sugar for the body to understand and process. The synthetic sugars are causing harm to some people, and promote diabetes.
Your’re talking about very rare cases where the diagnoses are known at birth. Those people already know enough not to ingest artificial sweetners. There’s a rare case for everything. By that standard people should be afraid to ingest almost everything.
Again Aspertame is safe for diabetics.