Actors tend to describe working on a long-running show with people as more like a family, or at least people they went to school with for years. A co-worker for most of us is someone who works down the hall and you might not see every day. And you may not spend many years working with the same person. Working in a cast of a show is a much closer relationship and also a smaller group.
That doesn't mean every one in every cast always likes each other or gets along. But the better man realizes that when you are in a small team that works together on something and is successful for years and years, you owe some loyalty, gratitude and respect to the other people on your team.
And Winkler and Baio tried to help her as others in the cast tried. Sometimes there no help that works.