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To: Doctor Stochastic
Still no sign of the vector.

This is an increase of 10 suspected Ebola virus deaths in the 2 days since the last report. The reference to gazelle is probably to a small, dog-sized antelope also known as duiker, nowhere near as fast a runner as the East and South African gazelles. These are caught and eaten by chimpanzees, but gorillas do not eat meat, so their source of infection must be something else -- termites or insect larvae have been postulated.
4 posted on 02/14/2003 10:04:18 AM PST by Neuromancer
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To: Doctor Stochastic
As to the apparent conservation of the Ebola virus genome over time, the most viable explanation is that the virus circulates in an ecological niche in a host without a mammalian-type immune system, therefore there is very little selection for change.

And recall: the sequences that haven't changed are of the order of a few hundred bases, which is a bit little to go basing a whole new polymerase specificity on.

Perhaps Ebola is in a natural reservoir host in which there is very little selective pressure - perhaps due to its being an insect (or even a plant...?)

Just my $0.02 worth, who knows...
5 posted on 02/14/2003 10:30:33 AM PST by Neuromancer
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