Not as much as you think. The Paris Bible in Latin, which was published in the 13th Century, was plentiful enough to have become a stock reference for the thousands of itirnerant friars who went about preaching to the masses. Small enough to fit into the pocket of their habits, it was one of the first books to look like the ones we are familiar with. The quality of printing is amazing. I saw a copy in a church museum in Dallas. More than 700 years old, it looked very modern. Hard to believe it was handwritten.
My batty son Pat hand-writes reproductions of the typeface in his school workbooks, like the forgery group in "The Great Escape" replicating German ID cards. It's the weirdest thing.