It seems to me that sinners would most benefit from the Body and Blood of Christ. Jesus did, after all, hang out with sinners on occasion...
This would be interesting, since the last supper was not celebrated with sinners.
I’m sure that if Jesus intended the sacrament to be distributed to those who were in a state of practical separation, he would have invited many sinners.
Further, in John’s Gospel for example, Satan entered into Judas the moment he ate with Jesus in the Gospel of John, since he had already planned his betrayal. (John 13:21-29)
That's why we have Confession --- the Sacrament of Penance --- so they/we can prepare them/ourselves properly for Holy Communion. Repent, seek the mercy of Jesus, confess,with a firm intention of not continuing in sin -- - that's the touch one, for me as for anyone --- and then you can properly approach the Blessed Sacrament.