It is a false parameter to simply limit his name at Antichrist, and say that he is mentioned only once. Such a limitation appears intentional on your part.
He is the little horn and the prince in Daniel.
He is the man of lawlessness in 2 Thessalonians.
He is the beast in the Revelation.
He is the man of sin.
He is the son of perdition.
The profile given in Daniel time after time is that he appears, has a kingdom, boasts, makes trouble for the Jews, and then is suddenly stopped and replaced by God’s permanent kingdom.
And the first reformers had no problem calling the papacy the seat of Antichrist.
Or the popes, Antichrists...
If Rome has a terrorist attack, war, or a brutally harsh earthquake in the coming years and the Pope and Vatican have to move their headquarters for a time, maybe the first reformers were on to something.
Because the only logical place for the pope to set up camp, if not Rome, is Jerusalem.