Posted on 12/09/2023 4:53:43 PM PST by Lazamataz
Results:
A schematic overview of three activation pathways of the complement system is outlined in Figure 1. Regardless of the activation pathway, the enzymatic cascade generates C3 convertase, which cleaves the most abundant C3 protein, into C3b and C3a. As the key effector molecule of the complement system, C3b and its inactive fragment iC3b bind covalently to the cell membrane and opsonize the antigen for eventual phagocytosis. Subsequently, C3b binds to C3 convertase to form C5 convertase that generates C5b and C5a. The assembly of the terminal complement proteins (C5b, C6, C7, C8, C9) contributes to the formation of the membrane attack complex (MAC) that disrupts the cellular lipid bilayer of the extracellular materials including bacteria, viruses, and nanocarriers. Meanwhile, C3a and C5a act as potent inflammatory mediators [11]. The detailed mechanisms of the complement system are not within the scope of this paper, yet there are several excellent literature reviews focusing on this subject [21,32,33,34].
You’re too funny, Laz. :-)
I am veger
Free Republic is dwindling down these days. Once a major mover and shaker, it is slowly contracting in participation and influence.
Yet I will remain here, hopefully to write the very last line it publishes.
I will remain here, if only to be funny.
And it’s appreciated. I’ve noticed a decline myself.
Got to be better than most of the Marxist State Media today. Most could not pass middle school exams.
“bodice-ripper”
“...which cleaves” — At least it got the cleavage part right ;>)
Na it’s speaking Bidenese…you know, the thing.
I did and it returned results about ‘creating’. I was hoping ‘creatring’ was a unique concept apart, and I would learn something today.
I did consult the Bulwer-Lyton 2023 contest and discovered this gem:
John was a police officer, and Mary was a serial killer, and just like that you think you know how that’s going to end, don’t you; well, John lived in New York and Mary lived in London, and they were both moderately afraid of airplanes, so I bet you’re not feeling like the brightest crayon in the box right now.
and
The tall, slender seductress had Tom Pauley wrapped around her little finger, and she had James McGee hanging from a necklace, but the police were still waiting for the lab results to determine whose body parts she had used to make her earrings and that stunning tennis bracelet.
and
Elsie was seated by the window overlooking the deserted boardwalk (the crime scene in this saga) holding the hand of her beloved Jeremy (the soon-to-be unwitting accomplice), when George (who you will soon learn is the murderer), suddenly opened the door to their cozy loft holding a cup of coffee and said, “This cup is for you, Elsie” —and this cup would of course be her last . . . but you do not know any of this yet.
The Story About Ping
PING! The magic duck!
Using deft allegory, the authors have provided an insightful and intuitive explanation of one of Unix’s most venerable networking utilities.
Even more stunning is that they were clearly working with a very early beta of the program, as their book first appeared in 1933, years (decades!) before the operating system and network infrastructure were finalized.
The book describes networking in terms even a child could understand, choosing to anthropomorphize the underlying packet structure.
The ping packet is described as a duck, who, with other packets (more ducks), spends a certain period of time on the host machine (the wise-eyed boat).
At the same time each day (I suspect this is scheduled under cron), the little packets (ducks) exit the host (boat) by way of a bridge (a bridge). From the bridge, the packets travel onto the internet (here embodied by the Yangtze River).
The title character — er, packet, is called Ping. Ping meanders around the river before being received by another host (another boat).
He spends a brief time on the other boat, but eventually returns to his original host machine (the wise-eyed boat) somewhat the worse for wear.
If you need a good, high-level overview of the ping utility, this is the book. I can’t recommend it for most managers, as the technical aspects may be too overwhelming and the basic concepts too daunting.
As good as it is, The Story About Ping is not without its faults. There is no index, and though the ping(8) man pages cover the command line options well enough, some review of them seems to be in order.
Likewise, in a book solely about Ping, I would have expected a more detailed overview of the ICMP packet structure.
But even with these problems, The Story About Ping has earned a place on my bookshelf, right between Stevens’ Advanced Programming in the Unix Environment, and my dog-eared copy of Dante’s seminal work on MS Windows, Inferno.
Who can read that passage on the Windows API (”Obscure, profound it was, and nebulous, So that by fixing on its depths my sight — Nothing whatever I discerned therein.”), without shaking their head with deep understanding. But I digress
That was brilliant. Did you generate it or did you ask AI to?
Prove me wrong.
This is what I got:
In “The Story of Ping,” Ping the duck faces the consequences of staying out late and getting separated from his family. Similarly, in network traffic, delays or disruptions can occur when data packets get separated or encounter obstacles on their journey across the network.
Ping’s adventures can be likened to the journey of data packets through a network. Just as Ping navigates the river and faces different challenges, data packets traverse various network devices, encountering routers, switches, and other elements that shape their path.
Much like Ping’s efforts to reunite with his family, network protocols and mechanisms work to ensure that data packets reach their intended destination efficiently and in the correct order. The concept of ‘ping’ in networking is also interesting—it’s a utility used to test the reachability of a host on an internet protocol (IP) network, drawing a parallel to Ping’s interactions and communication with other ducks in the story.
So, in a whimsical way, both involve journeys, interactions, and the importance of reaching the destination intact. Quite a unique comparison, isn’t it?
While I cannot prove you wrong (for you can never prove a negative) I can tell you that a plan was in place to deny Trump the election no matter what.
As it will be in 2024.
Laz: What ever became of Humblegunner?
Has it ever happened?
i think you got the default paragraph. congratulations. next up for you: the Hal 9000. good luck, sir.
AI should produce some new classical music.
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