Mathematician John Nash, 86, has been killed in a taxi crash on the New Jersey Turnpike along with his wife Alicia, 82 The pair were not wearing seltbelts and were ejected from the vehicle when their driver allegedly lost control and hit the guard rail Nash was widely regarded as one of the great mathematicians of the 20th century He was best known for his work on game theory and his struggle with paranoid schizophrenia The Nobel Prize winner was famously portrayed by Russell Crowe in the 2001 Hollywood movie A Beautiful Mind which won four Oscars