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A team of researchers is uncovering how the juice from red cabbage, long used in traditional medicine, can alleviate inflammation-associated digestive health conditions such as inflammatory bowel disease (IBD) in mice, offering hope to Americans who suffer from IBD, including Crohn's disease and ulcerative colitis. Santayana Rachagani's team found red cabbage juice boasts a diverse array of bioactive compounds that improved gut health and alleviated the symptoms of IBD in mice. "Red cabbage juice alters the composition of gut microbiota by increasing the abundance of good bacteria, resulting in increased production of short chain fatty acids and other bacteria derived...

Researchers have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis. This means the beginnings of inflammatory bowel diseases start a long time before symptoms occur, and in the future may provide an opportunity for doctors to take preventative action before symptoms begin, or prescribe medication when it will be most effective. Crohn's disease and ulcerative colitis are collectively known as inflammatory bowel diseases (IBD). They are incurable conditions which involve excessive inflammation in the gut, leading to symptoms...

The bubonic plague killed so many people in Europe, the Middle East, and North Africa that that natural selection event is still rippling through our genomes today. But the same genes that helped your ancestors survive the Black Death may be contributing to autoimmune disease today.Have an Autoimmune Disease? Blame the Black Death | 7:16SciShow | 7.77M subscribers | 572,860 views | November 7, 2023

Chronic bowel inflammation is based on an excessive or misdirected inflammatory reaction. Experts assume that the immune system also reacts incorrectly to microorganisms in the intestine that do not cause an inflammatory immune reaction in a healthy state. Now, researchers have discovered that yeast fungi could play an important role in this. Trillions of microorganisms colonize the human body, especially the intestine. This microbiome consists mainly of viruses and bacteria, but to a lesser extent also of fungi. However, according to current research, this interaction is disturbed in Crohn's disease, a chronic inflammatory bowel disease where the immune cells react...

The study found that 0.8% of same-sex patients with high-risk sexual activity were diagnosed with Crohn’s disease, while only 0.49 heterosexual men who engaged in high-risk sexual activity had Crohn’s disease. The research will enable the development of individualized, precision medicine for the management of inflammatory bowel disease in this underrepresented minority patient group. According to a recent study from Case Western Reserve University and University Hospitals Cleveland Medical Center (UH), gay men are more than twice as likely as heterosexual males to develop inflammatory bowel disease (IBD) when both groups participate in high-risk sexual activity. The study was recently...

Two new treatments for Crohn's disease showed roughly equal performance in a clinical trial. This allows clinicians and patients to make treatment choices based on tolerance, according to Stephen Hanauer, MD. Crohn's disease (CD) is a chronic, progressive inflammatory bowel disease, causing abdominal pain, weight loss and fatigue. Treatment for CD has typically focused on alleviating symptoms to achieve clinical remission using corticosteroids or immunomodulators, but a need for more effective treatment remains. "While there are numerous therapies and mechanisms of action for drugs approved for moderate-severe Crohn's disease there has been a therapeutic ceiling as far as outcomes are...

Research by the University of North Carolina at Chapel Hill and an international team traces the toxic impact of a common consumer product on the gut microbiome and induces colitis. A new study conducted in mice demonstrates precisely how triclosan, an antimicrobial found in toothpaste, toys, and thousands of other products, can trigger gut inflammation. An international team of researchers led by the University of North Carolina at Chapel Hill, the University of Massachusetts Amherst and Hong Kong Baptist University identified the bacteria, and even specific enzymes, that trigger triclosan’s harmful effects. Moreover, studies in mice suggest these bacterial enzymes...

An international study of more than 50,000 people with irritable bowel syndrome (IBS) has revealed that IBS symptoms may be caused by the same biological processes as conditions such as anxiety. The research highlights the close relationship between brain and gut health and paves the way for development of new treatments. IBS is a common condition world-wide, affecting around 1 in 10 people and causing a wide range of symptoms including abdominal pain, bloating, and bowel dysfunction that can significantly affect people’s lives. Diagnosis is usually made after considering other possible conditions (such as Crohn’s disease or bowel cancer), with...

Greetings! I know there are freepers who have knowledge and experience in just about any area of interest, so I figured we could gather some info/input from you on various treatments/ success stories for Crohn's. I did a search and various interesting articles have been posted, perhaps some of you have other useful links you could share. Over a year ago our youngest was diagnosed with Crohn's disease. Not that there is ever a good time to become ill, but this has impacted her studies and immediate University plans. She has been under the care of a physician who has...

Abstract Interleukin-6 (IL-6) is a classic pro-inflammatory cytokine critical in mounting an effective immune response. It is secreted by a wide array of cell types; however, its effector cells are more restricted, owing to the fact that very few cells, except lymphocytes and hepatocytes, express the functional membrane IL-6 receptor thus reducing the number of IL-6-responsive cells. Trans-signalling, the shedding of the membrane-bound form of the IL-6 receptor into the local microenvironment, greatly increases the range of cells that can respond. IL-6 has been demonstrated to have a pivotal role in the pathogenesis of rheumatoid arthritis, Castleman’s disease and Crohn’s...

Stem cells may force Crohn's disease into retreat, say Long Island medical investigators who are embarking on a pioneering analysis that targets patients who've failed other therapies. Cases of Crohn's disease have skyrocketed since World War II, jumping tenfold in the United States and raising questions about the disease's genetics and demography. It is one of two disorders -- the other is ulcerative colitis -- that are known as inflammatory bowel diseases. Before the 20th century there was no recorded evidence of either. Dr. Robert Richards, director of clinical research in the gastroenterology division at Stony Brook University Medical Center,...

Tysabri was pulled from the market in 2005 after three patients in clinical trials contracted a brain infection known as progressive multifocal leukoencephalopathy, and two patients died. Two patients were also taking Avonex. However, the FDA allowed the drug to return to the market in 2006 with a risk-management program. Crohn's disease is a chronic, progressive disease marked by inflammation of the bowel. The condition often causes abdominal pain and bleeding and can require surgery to remove diseased portions of the intestine. About 600,000 Americans have the disease. It wasn't immediately clear if there are any conditions attached to Tysabri's...

Prayers needed!!M1-A2 in hospital with Crohn's. Went down(fainted dehydrated) 08/29/07. Doing better today but will be in hospital for 3-4 more days. He(age 17)was just diagnosed in July. We are just now leaning about this malady. Thanks!! Mom and Dad

With increasing frequency, American citizens and others from around the globe are experiencing newfound freedom from disease, affliction, and infirmity. Individuals' lives are forever changed with the strengthened faith and renewed hope that arise from healed bodies and physical restoration. These seemingly miraculous cures are the result of adult stem cell treatments. Yet the debates in the popular media tend to ignore and obscure the medical breakthroughs made by adult stem cell research--success that has conspicuously eluded embryonic stem cell treatments.[1]  Adult stem cells (or, more accurately, tissue stem cells) are regenerative cells of the human body that possess the...

That Gut Feeling : Scientists at St Georges hospital in London are claiming there is a link between Crohns disease - a debilitating digestive problem that affects more than 40,000 people in the UK - and drinking milk. Professor John Hermon-Taylor, a surgeon, and his team have reported finding minute traces of an organism known as myco-bacterium paratubercolosis in two thirds of the intestinal tissue removed from Crohns patients after surgery and although the National Dairy Council has disputed such claims on the basis of its own studies, the hospital researchers say they have also found the organism in supplies...

Friday, October 1, 2004 Crohn's disease, sick cows and contaminated milk Posted: October 1, 20041:00 a.m. Eastern By Chris Bennett © 2004 WorldNetDaily.com For issues that affect public health, it shouldn't matter who leads the government. When research uncovers the cause of a disease, or shows where our food technology is no longer adequate, public health agencies under the leadership of either party should step forward. When the agencies don't act, the effect is chilling. In the short term, some special interests are protected, some companies make short-term profits. In the long term, we all lose. But by far the biggest losses...

The clearest evidence yet that Crohn's disease is caused by a type of bacteria blamed for a similar animal disorder has been published by US researchers. Mycobacterium avium subspecies paratuberculosis (Map) was found for the first time in the blood of people with the disorder. Half of the 28 people with Crohn's tested positive for Map. Dr Saleh Naser, from the University of Central Florida, who led the research, said a large-scale study was needed. Crohn's disease affects 100,000 Britons and can cause a variety of symptoms from a lack of appetite to chronic diarrhoea and abdominal pain. The cause...

Curing Chronic Illness Can Be Used To Destroy Either Political Party Ladies and Gentlemen: I present to you the world's longest running, and greatest, medical blunder, the cures for incurable diseases, and the Second Coming of Christ. There are 120 million American's with chronic illness. In 1997, researchers at Yale University were studying the clustering of autoimmune disorders in 84 families with Antiphospholipid Antibody Syndrome (APLA). They stated then that if they knew what caused APLA they would know a lot more about many of the other chronic illnesses. At the same time, I was searching the Internet for information...