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A collaboration between researchers has looked into the efficacy and safety of psilocybin in patients with major depressive disorder. In a paper, the team finds a rapid onset of antidepressant effects, sustained reduction in depressive symptoms, and improvement in psychosocial functioning associated with a single 25mg dose of psilocybin administered with psychological support in patients with major depressive disorder (MDD). A randomized, double-blind, placebo-controlled, phase 2 trial was conducted at 11 research sites in the US between December 2019 and June 2022. It involved 104 adults diagnosed with MDD with moderate or greater symptom severity. Participants received either a single...

My 13 year old nephew has come to live with me, I am a widower and my brother's wife (his mother) is seriously ill and hospitalized. There is all kinds of crap I need to overcome to get him enrolled in the local public school and I am not sure it is in his best interests anyway. So I will be retiring at the end of the week and giving him the attention of one of the best instructors on the planet-- me.He asked me why I despised CNN and I told them their fear pornography was worse than standard...

Gen Z is searching for sad music on Spotify Technology SA more than any other generation, leading the streaming platform to dub the past few months a “bummer summer” for the youth. “Sad” is Gen Z’s most-searched term on Spotify globally, the audio service said in a blog post Monday. In comparison, it’s the 13th most-searched term for Millenials. “To match the vibe in the US and Canada,” Spotify said it’s added new “sad” playlists and even installed a fountain of tears shaped like the artist d4vd in Houston, Texas.

Our long slide toward economic oblivion continues, and survey after survey has shown that most Americans are deeply unsatisfied with the current state of the U.S. economy. Inflation is out of control, most Americans are getting poorer due to the rapidly rising cost of living, the housing bubble has started to burst, and the commercial real estate market is a giant mess. But employment is supposed to be our bright spot. The Biden administration continues to tell us that the unemployment rate is less than 4 percent and that there are lot of jobs available for those that want them....

he much-anticipated recession of 2023 has yet to materialize. Some of the latest economic data point to more signs of strength than weakness. One strategist has a term for what that says about the state of the US economy. "We're calling that a rolling recession," David Bailin, chief investment officer at Citi Global Wealth Investments, told Yahoo Finance. He explained how some sectors of the economy are already in decline, while others, like travel and leisure, are still strong. "Clearly commercial real estate is in recession," he said. "Some of our manufacturing, basic consumer manufacturing is in recession right now."

Money supply growth fell again in April, plummeting further into negative territory after turning negative in November 2022 for the first time in twenty-eight years. April's drop continues a steep downward trend from the unprecedented highs experienced during much of the past two years. Since April 2021, money supply growth has slowed quickly, and since November, we've been seeing the money supply repeatedly contract—year-over-year— for six months in a row. The last time the year-over-year (YOY) change in the money supply slipped into negative territory was in November 1994. At that time, negative growth continued for fifteen months, finally turning...

Americans are pulling hundreds of billions of dollars out of banks at the fastest pace in nearly 39 years as many economic experts are beginning to predict a repeat of the 2008 “Great Recession.” According to an analysis of the most recent data from the Federal Deposit Insurance Corporation (FDIC), “depositors took a total of $472 billion out of their accounts in the first quarter of this year – shattering a 39 year record,” the Daily Hodl reported. “The quarterly decline is the largest reduction reported in the QBP since data collection began in 1984. This was the fourth consecutive...

A new study published 14 June in JAMA Psychiatry has found evidence that supplementing the diet with a probiotic blend containing 14 strains of bacteria can help individuals who are being treated for major depressive disorder with antidepressants. The research, led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London and in partnership with ADM Protexin, part of ADM, demonstrated the potential of probiotic supplementation to support improvements in multiple depression and anxiety scores over an eight-week period. The pilot study is one of the first trials in a Western population to show both good tolerability...

We know America is experiencing a mental health crisis, but the Youth Risk Behavior Survey recently released by the Centers for Disease Control and Prevention (CDC) illustrates just how serious the problem has become for America’s young people. In 2021, almost three in five teenage girls felt persistent sadness.

The Daily Mail contacted the Euthanasia Prevention Coalition wondering about our projections for the number of Canadian euthanasia deaths in 2022. EPC has published articles reporting the number of 2022 euthanasia deaths in Ontario, Alberta, Manitoba, Québec and recently we found the Nova Scotia data. Based on the known data I suggested that there were likely 13,500 Canadian euthanasia deaths in 2022. The article by James Reinl, the social affairs columnist for the Daily Mail reported the following on June 7: Canada has seen another record-busting year of euthanasia deaths, with a 35 percent rise to some 13,500 state-sanctioned suicides...

A mother of three is making international headlines for her ‘ability’ to communicate with the dead relatives of her now-famous clientele.Chloe Smith, 25, claims to be able to see angels and talk to the spirits of the dead.

Stanford researchers have discovered that certain brain signals actually flow the wrong way in people with treatment-resistant depression — and that magnets can correct the misdirection and help patients feel better. “This is the first time in psychiatry where this particular change in a biology — the flow of signals between these two brain regions — predicts the change in clinical symptoms,” said Nolan Williams, senior author of a paper detailing the discovery. The challenge: While most people living with depression can find some relief with medications, approximately 84 million people globally have treatment-resistant depression, meaning they still don’t feel...

A Columbia University study has found that teens who use cannabis recreationally are two to four times as likely to develop psychiatric disorders, such as depression and suicidality, than teens who don’t use cannabis at all. The research, published in JAMA Open Network(link is external and opens in a new window) May 3, also finds that casual cannabis use puts teens at risk for problem behaviors, including poor grades, truancy, and trouble with the law, which can have long-term negative consequences that may keep youth from developing their full potential in adulthood. "Perceptions exist among youth, parents, and educators that...

The percentage of U.S. adults who report having been diagnosed with depression at some point in their lifetime has reached 29.0%, nearly 10 percentage points higher than in 2015. The percentage of Americans who currently have or are being treated for depression has also increased, to 17.8%, up about seven points over the same period. Both rates are the highest recorded by Gallup since it began measuring depression using the current form of data collection in 2015. The most recent results, obtained Feb. 21-28, 2023, are based on 5,167 U.S. adults surveyed by web as part of the Gallup Panel,...

I used the link above but I mostly want to see if others are slow at work. We sell processing equipment to the food, pharma and plastic industries. We're dead---slower than 2016 and it's getting worse. Our shop is going to 4 day work weeks with no overtime allowed and most likely we will have layoffs in the office. I have been here for 35 years and have never seen it this slow. Heck, this company started during the great depression---if this keeps up it will be closed in a matter of 6 months. Our competitors and customers are saying...

By the summer of 1563, all of Britain had plunged into chaos over religion and the Reformation. King Henry VIII broke away from the Catholic church back in the 1530s, sparking a near civil war within the kingdom. Protestants killed Catholics, Catholics killed protestants, and extreme social tensions lasted for decades. Universities were at the heart of this conflict; rather than focus on real subjects like science and mathematics, students and professors became radical social activists and turned their schools into ideological echo chambers. Sound familiar? One of the few students who actually wanted to learn was a Scottish teenager...

WASHINGTON — The U.S. economy slowed sharply from January through March, decelerating to just a 1.1% annual pace as higher interest rates hammered the housing market and businesses reduced inventories. Thursday’s estimate from the Commerce Department showed that the nation’s gross domestic product — the broadest gauge of economic output — weakened after growing 3.2% from July through September and 2.6% from October through November. The slowdown reflects the impact of the Federal Reserve’s aggressive drive to tame inflation, with nine interest rate hikes over the past year. The surge in borrowing costs is expected to send the economy into...

Heeere we goooo. Fingers toes and eyes crossed for a successful test flight of the 33-Raptor engine Superheavy booster and Starship first time into space. Both vehicles are planned to splash down...the booster in the Gulf of Mexico and Starship off of Hawaii.

If virtually everyone is expecting a recession, and most people start acting accordingly, do you think that will make an economic downturn less likely or more likely? Needless to say, the answer to that question is obvious. Right now, banks all over the country are getting really tight with their money, large corporations are laying off workers at a frightening pace, and consumers are cutting back on their spending. In other words, it really is starting to look a lot like a recession out there, and economic conditions are only going to get even more harsh in the months ahead....

Children of politically liberal parents are more likely to suffer from depression and anxiety , lack a sense of life meaning, and have substance abuse issues, according to a family physician with more than 30 years of experience. Dr. Leonard Sax, who also holds a Ph.D. in psychology, told the Washington Examiner that left-of-center parents are much more likely to be "aggressively permissive" in their parenting style, leaving children without proper authority. These "permissive parents," whose parenting style is also known as "gentle parenting," do not want to be seen as "controlling" or "coercive" to their children. For example, "gentle...