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Novo Nordisk is the maker behind Ozempic and WegovyThe price of Novo Nordisk's blockbuster diabetes and weight loss-related drug Ozempic will be cut, according to President Donald Trump. Trump said this week during a White House event on fertility treatments and drug pricing the price reduction will come after swift negotiations with the drugmaker. "They'll be much lower," Trump told reporters. Novo Nordisk is the maker of Ozempic and Wegovy, which have the same active ingredient, semaglutide, but they are approved for different uses. Ozempic was approved by federal health officials in 2017 and marketed for medical use in the...

A study indicates that changes in the body that lead to type 2 diabetes occur long before current diagnostic thresholds for prediabetes are met. The study challenges conventional thinking about the onset of type 2 diabetes, identifying a risk category before prediabetes, called "pre-prediabetes." At this stage, people with normal glucose tolerance already have severe insulin resistance, early beta cell dysfunction and measurable cardiovascular disease. In this study, DeFronzo's team of scientists examined people with normal glucose tolerance, per ADA standards, and found that one measurement—one-hour glucose levels during an OGTT—is far better at predicting future disease. A value between...

In women with type 2 diabetes (T2D), use of hormone replacement therapy (HRT) skin patches is not associated with a higher risk of blood clots or stroke. However, an increased cardiovascular risk was found for oral HRT, according to a large real-world study. Among the findings are an analysis revealing women with T2D who took the oral form of HRT doubled their risk of developing a pulmonary embolism (PE—when a blood clot blocks an artery in the lung) and faced a 21% increased risk of heart disease compared with those receiving transdermal HRT (skin patches). "Our study suggests that up...

The wines named in the lawsuit are primarily inexpensive white or blush varietals including moscato, pinot grigio and sauvignon blanc.Many popular, inexpensive brands of wine made and distributed in California, including Trader Joe's famed "Two Buck Chuck," contain illegal and dangerously high levels of poisonous inorganic arsenic, according to a lawsuit filed Thursday in Los Angeles. Plaintiffs Doris Charles, Alvin Jones, Jason Peltier and Jennifer Peltier allege in their complaint that dozens of wineries are violating state law by knowingly producing, marketing and selling arsenic contaminated wine and failing to warn consumers about the potential danger. The suit, filed in...

Img src="https://scitechdaily.com/images/Marijuana-Leaf-Cannabis-Buds-Chocolate-Brownies-Edibles-777x518.jpg"> annabis use may secretly quadruple your risk of diabetes. Credit: Shutterstock Cannabis use may come with an unexpected cost: a nearly fourfold rise in diabetes risk. The finding, drawn from millions of health records, challenges assumptions about the drug’s effects and underscores the need for closer medical monitoring. Cannabis Use and Diabetes Risk Cannabis use has been associated with nearly a fourfold increase in the likelihood of developing diabetes, according to an analysis of health data from more than 4 million adults. The findings are being presented at this year’s Annual Meeting of The European Association for the...

The widely used diabetes drug metformin changes blood metal levels in humans. The study is an important step in understanding the drug's many actions and designing better ones in the future. Metformin is the most widely prescribed diabetes drug in the world. Apart from lowering blood sugar levels, it is also known to have a broad range of beneficial side effects such as against tumors, inflammation and atherosclerosis. However, although it has been used for more than 60 years now, its mechanism of action is still not clear, hampering the development of even better drugs against these conditions. Ogawa Wataru...

WASHINGTON (AP) — Global warming in the United States is amping up the country’s sweet tooth, a new study found.When the temperature rises, Americans — especially those with less money and education — drink lots more sugary beverages and a bit more frozen desserts. It amounts to more than 100 million pounds of added sugar (358 million kilograms) consumed in a year, compared to 15 years earlier, according to a team of researchers in the U.S. and United Kingdom writing in Monday’s Nature Climate Change.

Potatoes have long had a bad rap for being high in carbs. A new study backs that concern—at least in part.That weekly french fry habit could be setting you up for diabetes decades down the road. Research found that eating french fries just three times a week may significantly raise Type 2 diabetes (T2D) risk—but, surprisingly, other potato preparations showed no increased risk at all.RaraAvisPhoto/Shutterstock“Our findings suggest it’s not fair to put all potatoes in the same basket,” lead author Seyed Mohammad Mousavi told The Epoch Times.How You Like Your Potatoes MattersThe study, led by Harvard T.H. Chan School of...

Kidney complications in diabetes often progress silently, putting patients at risk of life-threatening outcomes long before any symptoms appear. A new study offers a promising solution. Researchers found that two simple blood markers—estimated glomerular filtration rate difference (eGFRdiff) and growth differentiation factor-15 (GDF-15) levels—can independently predict kidney disease progression and mortality in people with diabetes. "Currently, eGFR and urinary albumin, which are commonly used in routine clinical practice, are not sufficient to accurately predict kidney outcomes in individuals with diabetes," says Dr. Gohda. The research team analyzed data from 638 Japanese adults living with diabetes mellitus. Participants were observed for...

A study has found that drinking just one can of artificially-sweetened soft drink a day may increase the risk of developing type 2 diabetes by 38%. Surprisingly, that risk for artificially sweetened soft drink is even higher than for those who consume sugar-sweetened beverages, such as regular soft drinks, where the risk was found to be 23% higher. The research followed more than 36,000 Australian adults over nearly 14 years. The study—led by Professor Barbora de Courten, Associate Professor Allison Hodge, and Ph.D. student Robel Hussen Kabthymer—adds to growing global concern about the health effects of both sugary and artificially...

A team has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor–induced type 1 diabetes, a rare but life-threatening side effect of cancer immunotherapy, using an existing class of autoimmune drugs. The study identifies a new group of immune cells involved in the development of immune checkpoint inhibitor–induced type 1 diabetes and shows that JAK inhibitors, which are already FDA-approved for conditions like psoriasis and arthritis, can stop the autoimmune attack on insulin-producing cells in the pancreas and, in some cases, even reverse the damage in preclinical models. Checkpoint inhibitors like pembrolizumab and nivolumab have revolutionized...

It’s no secret that kids (and some of us adults) love fruit juice. Many of us grew up drinking fruit juice, and parents often think 100% fruit juice is healthy. But is it really? UC Davis Health pediatricians Lena Rothstein and Dean Blumberg tackled this juicy topic in their podcast Kids Considered: We often like the taste of fruit juice because it’s a sweet drink. But it’s no secret that sweet often means more sugar, even if it’s natural sugar. Think about whole fruits that are sweeter – they have more natural sugars that make them taste sweet. Same goes...

The health benefits of potatoes are misunderstood, according to research by professor Neda Akhavan in UNLV’s Department of Kinesiology and Nutrition Sciences. Nutrition sciences professor Neda Akhavan’s recent research identifies potatoes as a potential superfood for individuals with Type 2 diabetes. New research reveals that properly prepared potatoes can offer significant health benefits, including cardiovascular improvements, for people with Type 2 diabetes, challenging their negative dietary reputation. The potato is small enough to fit inside a person’s hand yet contains enough nutrients to whittle waistlines and lower blood sugar in adults with Type 2 diabetes. Yet, despite the fact that...

Despite medical advances, infectious diseases caused by bacteria and viruses are still among the most common causes of death worldwide. What role could fructose play in such diseases? A research group has now been able to prove for the first time that monocytes, important immune cells in the blood, react more strongly to bacterial toxins after fructose consumption—but not in a positive way. Specifically, the concentration of receptors for certain bacterial toxins increases, making the body more susceptible to inflammation. In two independent randomized studies with healthy adults, the researchers investigated how the consumption of fructose-sweetened beverages affects the immune...

My doctor just prescribe Metformin for Type II diabetes. He says I'm borderline but I'm hoping to control it via diet vs. medicine. My question is what have other Freepers with T II done? How many carbs do you limit yourself too each day? Recipes? What other things should I be thinking about? I walk 1.5 to 5 miles per day and I'm pretty sure I can control it via diet as I have a sweet tooth. I've done the Aikens diet in the past and had luck, is that a route others have taken? My recollection was to get...

A common diabetes drug can reduce the pain of people with knee osteoarthritis and overweight or obesity, possibly delaying the need for knee replacements, research has found. Metformin, which is commonly prescribed to treat type 2 diabetes, reduced knee arthritis pain over six months in a clinical trial. The research was performed as a community-based study using telehealth. Some of the 107 participants with pain from knee osteoarthritis, who had a mean age of 60, took up to 2,000 mg of metformin daily for six months. Others took the placebo. None had diabetes. Knee pain was measured on a 0–100...

The ‘Modern Family’ alum tells PEOPLE that he was initially "embarrassed" about his type 2 diabetes and kept his diagnosis a secret from friends and family Eric Stonestreet used to think his health was “fairly good.” He struggled to lose weight like many people, but felt fine overall. “I was just trying to maintain as healthy a lifestyle as I could without doing a tremendous amount about it,” he tells PEOPLE. But in 2009, just as he landed his beloved role as Cameron Tucker on Modern Family, Stonestreet was diagnosed with type 2 diabetes. “It was like this crazy happy...

Scientists may have identified a way to naturally regulate blood sugar levels and sugar cravings in a similar fashion to drugs like Ozempic. In mice and humans, the key to unlocking this natural process was found to be a gut microbe and its metabolites – the compounds it produces during digestion. By increasing the abundance of this one gut microbe in diabetic mice, researchers led by a team at Jiangnan University in China showed they can "orchestrate the secretion of glucagon-like peptide-1". Glucagon-like peptide-1 (GLP-1) is a hormone that is naturally produced by the body and which helps regulate blood...

In a study, researchers examined the possible links between exposure to mixtures of commonly consumed food additives and the onset of type 2 diabetes. Two out of the five mixtures tested were found to be associated with a higher incidence of type 2 diabetes. To measure the consequences of exposure to these mixtures, a research team analyzed the health data of 108,643 adults over an average follow-up period of 7.7 years. The participants completed at least two days (up to 15 days) of online dietary records of all food and drink consumed and their brands. In order to obtain a...

Researchers conducted a large-scale epidemiological study to explore the potential health benefits of high muscle strength in preventing type 2 diabetes (T2D) across varying levels of genetic risk. The study found that higher muscle strength was associated with over 40% lower risk of T2D, regardless of genetic susceptibility to T2D. The study highlights the importance of maintaining or improving muscle strength for preventing T2D. The research utilized data of 141,848 white British individuals without baseline T2D from the UK Biobank. Muscle strength was assessed in the form of grip strength. Genetic risk of T2D was estimated based on 138 known...