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In the stomach, parietal cells are responsible for acid production. They react not only to the body's own messenger molecules, but also to bitter-tasting food constituents such as caffeine. A research team has now carried out a study on a human gastric cell line. Their results help to clarify the molecular regulatory mechanisms by which bitter substances influence gastric acid production. It is known that taste receptors for bitter substances are not only found on the tongue, but also on the surface of other tissues and cells. These include the parietal cells of the stomach, which secrete protons into the...

Scientists have discovered a potential target for gastric cancers associated with Epstein-Barr Virus. In the paper, Wistar's Tempera lab investigates the epigenetic characteristics of gastric cancer associated with the Epstein-Barr Virus: EBVaGC. Italo Tempera, Ph.D. and collaborators demonstrate that an epigenetically active compound called decitabine disrupts the genome of EBVaGC by epigenetically modifying the cancer's DNA. "What we have identified is essentially a self-destruct button within this kind of cancer, and our paper shows that we figured out how to press that self-destruct button," said Tempera. "Normally, a latent virus that reactivates and starts to kill cells is a bad...

was an English major...you do the math! ;-) Unless you're in even worse mathematical shape than I am, you probably don't need to have it pointed out to you that this is part 2 of a 2-part blog post. Just in case you missed part 1, you should probably check it out first so you aren't totally lost...and so you don't miss out on a few cute pictures of my kids and grandkids! You would NOT want to miss those! OK...here are a couple pictures of some of my cuties just for fun: Here are Jayla and Asher, enjoying Sammi...

Medical experts confirm that a procedure known as gastric bypass surgery can lead to dramatic improvements to weight and overall health. . . . . In the case of government obesity, the bypass would entail the detachment of the fiscal alimentary tract from the endless entrails of superfluous federal agencies, where trillions of taxpayer funds are currently absorbed and excreted in wasteful government programs. Instead, a new incision would be made just below the gullet of the IRS and revenue would be routed exclusively to essential functions -- those that provide for the common defense, promote the general welfare and...

The 322-pound, redmeat-loving Dorchester dad who stuffed his face with pizza, steak tips, prime rib and fast food in a final fling before stomach-shrinking surgery, found out yesterday that the gravy train has reached the end of the line. His surgeon won’t operate until he drops 40 pounds and gains some new perspective. “It couldn’t have went any worse,” said Chris “Tiger” Stockbridge, 34, who claims he’s a changed man, finally ready to follow doctor’s orders and submit to a life of oatmeal, salad and fish, if that’s what it takes. “I felt a little bit ashamed of myself,” he...