VlincRNAs Provide Clues to Genomic Dark Matter by Jeffrey Tomkins, Ph.D. * Scientists have known for several years that the human genome is pervasively copied into various RNA molecules (transcripts), although scientists have been unsure about what much of it actually does. New research shows that about 10 percent of the genome encodes a newly characterized type of regulatory molecules called "vlincRNAs."1 When scientists first completed a draft of the human genome, they discovered that it only contained about 20,000 to 25,000 protein-coding genes.2 However, researchers soon discovered that these protein-coding genes produced a vast array of RNA transcript variants...