IRVINE, Calif. — On the morning of Feb. 28, 2000, a man in a black hood ran up to Patrick Riley in front of his office, shot him flush in the face and fled. The bullet missed his brain, and Mr. Riley, a biotechnology entrepreneur, survived. But two days later, his business partner, a doctor named Larry C. Ford, killed himself with a shotgun after learning he was suspected of being the mastermind behind the shooting. That is where the story probably would have ended — a lurid but ultimately local piece of intrigue played out in the sun-splashed Orange...