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The COVID-19 pandemic has driven great interest in the therapeutic potential of repurposed drugs with well-established benefits and safety profiles (toxicity, bioavailability, etc.), many of which act via signal transduction pathways. One category of such drugs is those that reduce acid production in gastroenterological contexts. Acid-suppressing drugs belong to two main classes, based on their mechanisms of action: (i) proton-pump inhibitors (PPIs) sterically block H+/K+-ATPase pumps, impeding the final step of acid release in the gastric mucosa. (ii) Histamine H2 receptor antagonists (H2RA) competitively bind the H2R, a type of G-protein coupled receptor (GPCR),1 and block the natural stimulation of...

Since President Trump acknowledged he was taking hydroxychloroquine as a preventative measure, he’s been criticized by the left for taking and championing an “unproven” drug that could have serious side effects, as some physicians point out. But other doctors point to the fact that it’s been in use for decades to treat malaria, lupus and rheumatoid arthritis, and is a “very, very safe drug.” Some on the frontlines of the coronavirus fight say using HCQ as a therapeutic in treating COVID-19 has been a game changer.  In India, its use as a prophylaxis appears--so far--to be working. More than half of...

Over the weekend, the Food and Drug Administration (FDA) issued an emergency authorization for the use of hydroxychloroquine (HCQ) and chloroquine (CQ) to treat hospitalized COVID-19 patients. Simultaneously, the Department of Health and Human Services (HHS) announced that Sandoz has donated 30 million doses of HCQ and Bayer one million doses of CQ to the Strategic National

White House Unveils Free Preventative ServicesBY JANET ADAMY JULY 15, 2010 WASHINGTON—Treatments for the prevention of alcohol abuse, depression and obesity are among the services that will be free to consumers with new insurance plans starting in September. As part of the new health law, the Obama administration on Wednesday released rules specifying which preventive health services insurers must provide to consumers at no additional cost. Democrats hope the change will be one of the most popular early pieces of the sweeping legislation. "Services like these will go a long way in preventing chronic illness," First Lady Michelle Obama said...

I keep hearing Obama and Pelosi saying we need to increase preventative care to lower the cost of healthcare. I would concede the point that preventative care can potentially improve the quality and length of one’s life, but how does it lower healthcare costs in the long run? Isn’t someone who takes great care of his or herself going to require more healthcare over their life than someone who eats fast food every day and drops dead of a massive coronary at age 50. Does preventative care prevent death? Well until it does, I have to assume we will all...

I would not argue that preventative care doesn't make sense on a personal level for an increased quality of life, but as a means of reducing healthcare costs ala Obamacare, it makes no sense....unless.... the plan is to postpone serious illness in people until they are old enough to be only deemed worthly of recieving Obama's Pain Killer Therapy... Otherwise, from a financial point of view, preventative care is only postponing the inevitable. We can't prevent what ever terminal sickness or disease we will each eventually contract, assuming you don't get hit by a bus first, we can only postpone...

Public Health (from a German Propaganda pamphlet authored by Walter Tießle). "In preserving health, National Socialism is following fundamentally new ways of thinking. In the past, one understood health care as caring for those who were ill. Enormous means were used. And in certain circles, the ill were the model of humanity, at the center of all action and thought. No one made the effort to find the roots of illness, or to consider: "How could we stop illness at its start, or at least limit it as much as possible?" The means used by National Socialism must, of course,...

SAN FRANCISCO (AP) - Health professionals applauded the federal government for including people exposed to the HIV virus through isolated episodes of unsafe sex or drug use among those recommended for emergency treatment, calling the new policy an overdue surprise from the Bush administration.Previously, federal health officials advised a preventative 28-day regimen of AIDS drugs only for health care workers accidentally exposed on the job. But the Centers for Disease Control and Prevention expanded its guidelines Thursday, saying rape victims, as well as some individuals who knowingly put themselves at risk, should receive the drug cocktail that can keep them...