Free Republic

Research led by Nicolas Bazan, MD, Ph.D. suggests that age-related macular degeneration (AMD) decreases an essential fatty acid, preventing the formation of a class of protective molecules and reducing repair potential. The discovery may also open new therapeutic avenues for AMD. The study shows that AMD decreases peripheral retinal docosahexaenoic acid (DHA) 22:6 in rod photoreceptor cells, limiting the elongation of fatty acids to form very-long-chain polyunsaturated fatty acids (VLC-PUFAs). VLC-PUFAs are precursors of elovanoids, bioactive chemical messengers made from omega-3 very- long-chain polyunsaturated fatty acids. Elovanoids, discovered by the Bazan lab, have been shown to restore the structure and...

If you have been wearing glasses for years, like me, it can be surprising to discover that you perceive the world thanks to a few giant companies that you have never heard of. Worrying about the fraying edge of motorway lights at night, or words that slide on the page, and occasionally spending a fortune at the opticians is, for many of us, enough to think about. And spectacles are unusual things. It is hard to think of another object in our society which is both a medical device that you don’t want and a fashion accessory which you do....

Scientists are on the brink of restoring sight to the blind by sending moving images directly to the brain. In a world-first, surgeons have implanted a visual stimulator chip in the brain of a 30-year-old woman. The patient, who has been totally blind for seven years, saw coloured flashes, lines and spots when signals were sent to her brain from a computer. Her doctors are now planning to send footage from a tiny video camera to the brain, which could provide the world’s first bionic eye and restore sight to millions. The technology bypasses the eyes, meaning it has the...

Yesterday, at a neighbor's house, his 4th grade daughter read something very well and I asked her what grade she was in and complimented her on her reading .....

Just curious where other freepers get their contact lenses online? My tow kids are now both sporting contacts and I am looking for reputable sites that will deliver to my home for the best price. Can anyone lend their experience?

...endless shock waves of intellectual disorientation. Here is jargon concocted by our elite experts during this long national nightmare: psycholinguistics, miscue analysis, reading strategies, comprehension strategies, whole word, guessing, picture reading, whole language, sight words, balanced literacy, reading readiness, word walls, active learning practices, closed instructional activities, high-frequency words, thinking and learning about print, invented spelling, reading recovery, emergent literacy, creative curriculum approach, functional systemic linguistic theory, rich literacy activities, authoring cycle, capability beliefs, post-reading, lifelong reader, cognitive flexibility theory, independent reading, kid watching. The drift of all this malarkey is that reading is a very difficult thing to do.

More than 70,000 Minnesota homeowners were behind on their mortgages and received pre-foreclosure notices last year, a warning that the housing market still faces serious hurdles in 2011. About 71,665 struggling homeowners got the notices in 2010, up 8 percent from 2009, according to the Minnesota Home Ownership Center, which released the numbers Thursday. The number of notices rose 3 percent in the Twin Cities metro area, but 15 percent elsewhere in Minnesota. The numbers suggest that despite glimmers of hope in the job market, the state could see more people lose homes this year than they did last year,...

First Lt. Jason Hickman, of Greenville, W.Va., proudly holds Noor Hassam Oudah during a celebration in her honor, Dec. 9. The one-year-old, known as "Baby Nourah," was born blind with congenital cataracts. Hickman spearheaded a campaign, raising over $5,000 for her surgery through donations from Soldiers of the 150th Armored Reconnaissance Squadron, 30th Heavy Brigade Combat Team, and their families and friends. Baby Nourah received surgery through the Khalidi Medical Center in Amman, Jordan, Nov. 15, three days after her first birthday. Photo by Spc. Ruth McClary, 30th Heavy Brigade Combat Team. BAGHDAD — One-year-old Noor Hassam Oudah, known as...

Medical Columnist Mark Roberts look at our five senses, how they work and their importance...."What's that smell?"

"They're going to put it where?"

MELBOURNE, April 18, 2007 (LifeSiteNews.com) - A man's vision has been restored by a corneal patch grown from adult stem cells by a team at the University of Melbourne's Centre for Eye Research Australia (CERA) and the Bernard O'Brien Institute of Microsurgery (BOBIM). The patch, which replicates the cornea, was cultivated from a single stem cell from a donor eye and was transplanted to the surface of the man's eyes. The research team was led by Dr Mark Daniell (CERA) and Dr Erik Thompson (BOBIM). The process, known as a limbal stem cell transplant, is thought to be the first...

A team of Johns Hopkins neuroscientists has worked out how some newly discovered light sensors in the eye detect light and communicate with the brain. The report appears online this week in Nature. These light sensors are a small number of nerve cells in the retina that contain melanopsin molecules. Unlike conventional light-sensing cells in the retina—rods and cones—melanopsin-containing cells are not used for seeing images; instead, they monitor light levels to adjust the body's clock and control constriction of the pupils in the eye, among other functions.

WASHINGTON — Scientists are testing artificial retinas that they hope can restore partial sight to people who've lost their vision to the most common causes of blindness.

Mumbai: Seven years after its inception amid much fanfare, Reliance Life Sciences, or RLS, is finally rolling out stem cell-based therapies in India, beginning with a treatment that can restore or improve vision. “This is the first commercial stem cell treatment in ophthalmology in the country,” said K.V. Subramaniam, CEO and president, RLS, part of the Mukesh Ambani-led Reliance group. The company, which has invested around Rs1,000 crore in the business, has lined up other stem cell therapies for cardiac infarction, diabetic ulcer, and stable vitiligo or leukoderma (a skin disease), among others, to be offered in clinics in the...

iZumi Bio has agreed to license some patents from the J. David Gladstone Institutes as they begin to work together on new adult stem cell technology involved in devising cardiovascular therapies. ReportStem cell transplants were used to restore the sight of six blind patients at a London hospital. StorySome 2,500 delegates attended the recent International Society for Stem Cell Research in Philadelphia. And insiders say that the development of induced pluripotent stem cells has clearly energized the entire field. ReleaseIn a new study regarding age-related diseases, researchers identified two key regulatory pathways that control how well adult stem cells...

MOUNTAIN HOME, Ark. — When 9-year-old Kacie Sallee saw her father's face more clearly for the first time in her life, she had a question. "She said, 'Is that what he looks like?'" said her mother, Marinda Sallee. Kacie, who is blind, returned last week from China, where she received umbilical-cord stem cell treatment in hopes of improving her eyesight. The nearly four-week trip and medical treatment was paid through $60,000 in local donations. Kacie was born with septo-optic dysplasia, an underdevelopment of the optic nerve and pituitary gland. She could see bright colors out of her right eye but...

The pharmaceutical giant Pfizer has announced that it is funding a new adult stem-cell treatment that could treat diabetes-induced retinal damage, a leading cause of blindness. Forbes Magazine says that Pfizer is funding the creation of a San Diego biotech company named EyeCyte to develop stem-cell treatments for eye diseases. The company will base its work upon Scripps Research Institute ophthalmologist Martin Friedlander’s research involving stem-cells from blood and bone marrow. EyeCyte will receive about $3 million from Pfizer, which in return has the right of first refusal regarding the new company’s products. In animal experiments, adult stem-cells have shown...

The patient was blind. Maguire's hair-thin needle traveled through the "white" of his eye, all the way back to his badly scarred retina, where it would deliver billions of genetically modified viruses. Each virus carried a single gene: the recipe to produce a crucial enzyme that his eye was unable to make on its own. Within weeks, beyond what anyone had predicted, the experiment worked. The young man and two other patients began to regain some vision. The results, reported online today by the New England Journal of Medicine, represent a dramatic advance in the field known as gene therapy,...

Former Cork club hurler Jimmy Aherne wept when he was told he would be blind within three years. The father-of-four -- who is a second cousin to hurling legend Christy Ring -- was diagnosed with age-related macular degeneration (AMD). The condition is cruel, as it has traditionally been untreatable. For decades, thousands of pensioners who lost their sight were simply told they had "old people's blindness" and that nothing could be done for them. But today, almost 12 months after that shocking diagnosis, the deterioration in Jimmy's eyesight has been halted and his good eye has improved to the point...

Stem cells derived from bone marrow and intrastromally injected into the corneas of mice can differentiate into keratocan-producing cells, according to an experimental study by researchers at the University of Cincinnati. Winston Whei-Yang Kao, PhD, and colleagues investigated whether bone marrow stem cells could differentiate into cells that expressed keratocan, a characteristic of corneal keratocytes. The study involved Kera-/- mice. Hongshan Liu, PhD, a research scientist in the university's ophthalmology department, presented their findings at the Association for Research in Vision and Ophthalmology meeting. The researchers found that, after 1 week, the abnormal corneas of animals injected with the stem...