Gastric bypass makes gut burn sugar faster

Nature News ^ | 25 July 2013 | Heidi Ledford

[neverdem]

Diabetic rats control blood glucose better after weight-loss surgery.

A procedure increasingly used to treat obesity by reducing the size of the stomach also reprogrammes the intestines, making them burn sugar faster, a study in diabetic and obese rats has shown.

If the results, published today in Science1, hold true in humans, they could explain how gastric bypass surgery improves sugar control in people with diabetes. They could also lead to less invasive ways to produce the same effects.

“This opens up the idea that we could take the most effective therapy we have for obesity and diabetes and come up with ways to do it without a scalpel,” says Randy Seeley, an obesity researcher at the University of Cincinnati in Ohio, who was not involved in the work.

As rates of obesity and diabetes skyrocket in many countries, physicians and patients are turning to operations that reconfigure the digestive tract so that only a small part of the stomach is used. Such procedures are intended to allow people to feel full after smaller meals, reducing the drive to consume extra calories. But clinical trials in recent years have shown that they can also reduce blood sugar levels in diabetics, even before weight is lost2, 3.

“We have to think about this surgery differently,” says Seeley. “It’s not just changing the plumbing, it’s altering how the gut handles glucose.”

Work-around
Nicholas Stylopoulos, an obesity researcher at the Boston Children’s Hospital in Massachusetts, and his colleagues decided to learn more about this mechanism by studying one of the most popular weight-loss procedures, the Roux-en-Y bypass. The surgery reduces the stomach to about the size of a hen's egg, and rearranges the intestines into the shape of a Y. The arm of the Y that is connected to the reduced stomach...

[Chickensoup]

You are stupid

I have an adopted daughter with a syndrome that causes large muscles and gut obesity. it is normative.

She eats normal portions.

She was and is an athlete

You continue to be stupid

[VeniVidiVici]

Roux-en-Y gastric bypass is the last thing I would recommend because it is not in accord with normal physiology. Someone needs to compare the results with gastric banding.

I believe because the Roux-en-Y is believed to be useful of getting rid of diabetes first with a secondary of reducing weight. And they don't know why. As opposed to a simple band which targets weight reduction.