http://wwwnc.cdc.gov/eid/article/15/8/08-1511_article.htm
Bordetella pertussis Strains with Increased Toxin Production Associated with Pertussis Resurgence
“In the 1990s, a resurgence of pertussis was observed in a number of countries with highly vaccinated populations, and pertussis has become the most prevalent vaccine-preventable disease in industrialized countries. We present evidence that in the Netherlands the dramatic increase in pertussis is temporally associated with the emergence of Bordetella pertussis strains carrying a novel allele for the pertussis toxin promoter, which confers increased pertussis toxin (Ptx) production. Epidemiologic data suggest that these strains are more virulent in humans. We discuss changes in the ecology of B. pertussis that may have driven this adaptation. Our results underline the importance of Ptx in transmission, suggest that vaccination may select for increased virulence, and indicate ways to control pertussis more effectively.”
Interesting. I wonder if they have adapted the recipe to account for the changes? The underlying reason for vaccination is still valid.
Important point: it is probably not a coincidence that many people in my area are opting out of the vaccination. My son’s doctor has been tracking the incidences and the numbers of people not getting the vaccination. There are stats although specific information might not be available. Anyway, he seemed pretty convinced.
Also, I wonder if the incidences have increased elsewhere or just in my area. I got the impression that it was localized.
BTW, my doctor is from India. :)
Anyway, I’ll mention this reference to him. Thanks.
Here is an interesting bit of info from the same article.
“Before childhood vaccination was introduced in the 1940s, pertussis was a major cause of infant death worldwide. Widespread vaccination of children succeeded in reducing illness and death.”
So apparently, the reason for vaccination is sound.