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Ozone reaction with skin causes irritants
Chemistry World ^ | 18 August 2009 | Jon Cartwright

Posted on 08/19/2009 8:36:20 AM PDT by neverdem

Ozone found in indoor environments reacts with human skin, potentially producing chemicals that irritate the skin and lungs, according to researchers in Austria and the US. The study, which is the first of its kind to be performed with humans, highlights the limitations of current methods used to assess indoor air quality.

Trioxygen, or ozone, is present in low levels throughout the Earth's atmosphere. Ozone can find its way indoors, although it is also emitted by many devices including photocopiers and air cleaners. For this reason, past studies have investigated the effect of ozone in the office environment. However, these have all focused on ozone's chemistry with materials and consumer products, and not on its chemistry with humans.

Now, Armin Wisthaler of the Leopold-Franzens University of Innsbruck, Austria, and Charles Weschler of Rutgers University in New Jersey, US, have performed a study of ozone with human occupants in an office environment. They used a technique called proton transfer reaction-mass spectrometry (PTR-MS), which can monitor volatile organic compounds (VOCs) in real time. It works by sending a sample of air through a tube of H3O+ ions, which donate protons to the VOCs, leaving them ionised. With input of standard reaction-rate constants, PTR-MS can calculate each VOC's original concentration.

Wisthaler and Weschler performed tests with two human subjects in a 28.5m3 chamber, designed to simulate an office, with normal ozone levels of about 15 parts per billion. They discovered a range of VOCs, including three types of dicarbonyls and two alpha-hydroxy ketones which have not previously been reported in studies of air pollution. Past research suggests that some of the more volatile of these compounds might irritate the lungs, while some of the less volatile compounds might irritate the skin.

Compounds produced after reaction between squalene and ozone

Researchers identified a number of previously unreported compounds formed as a result of reactions between ozone and squalene (in the white box) on exposed skin

The newly identified compounds are likely to be produced when the ozone reacts with squalene, an organic compound, and unsaturated fatty acids, both of which are found on the human skin. The study suggested that a single human can remove up to a quarter of all ozone in a similar-sized office via this reaction.

However, the study may also have implications for methods of outdoor air-pollution analysis. Squalene and fatty acids are also found on various outdoor surfaces, including plants, buildings and the sea surface, and so have the potential to react with ozone here too. 'To a large extent, the resultant products are likely to have been overlooked in surveys of outdoor pollutants for the same reasons that they have been overlooked in indoor pollutants - analytical methods have been used that were not suited to the detection of easily oxidised or highly functionalised compounds,' the researchers note.

References

A Wisthaler and C J Weschler, Proc. Natl. Acad. Sci., 2009, DOI: 10.1073_pnas.0904498106

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TOPICS: Health/Medicine
KEYWORDS: ozone

1 posted on 08/19/2009 8:36:20 AM PDT by neverdem
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To: neverdem; Safrguns

Neverdem, IIRC Safrguns knows a few things about ozone.

*Ping* Safrguns ...sounds like your territory


2 posted on 08/19/2009 8:40:38 AM PDT by Daffynition ("...... we are about to be czarred and fettered." ~ alterum ictum faciam.)
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To: neverdem
Squalene?

Isn't that , or a derivative, what was in vaccines that made people sick?

3 posted on 08/19/2009 8:54:06 AM PDT by norraad ("What light!">Blues Brothers)
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To: neverdem
I thought it said, "Obama reaction with skin causes irritants "

I really gotta get out more...;'}
4 posted on 08/19/2009 8:57:16 AM PDT by rockrr (Everything is different now...)
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To: neverdem
It's ironic that ozone was once considered beneficial to health.

The name "Ozone Park" was chosen to "lure buyers with the idea of refreshing breezes blowing in from the Atlantic Ocean to a park-like community."

(from Wikipedia article on Ozone Park, NY.)

The same was true of radon.

5 posted on 08/19/2009 9:22:32 AM PDT by hellbender
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To: neverdem

Ozone is used as a disinfectant in some sewage treatment plants because some consider it environmentally less damaging than chlorine. Makes you wonder what interesting organic compounds are coming out the effluent discharge.


6 posted on 08/19/2009 9:26:31 AM PDT by hellbender
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To: norraad
Squalene?

Isn't that , or a derivative, what was in vaccines that made people sick?

IIRC, squalene is an adjuvant not previously approved by the FDA in human vaccines, and an ingredient in one of the five swine flu vaccines being tested.

‘But it could end up being anything because one of the additives in one of the vaccines is a substance called squalene, and none of the studies we’ve extracted have any research on it at all.’

He said squalene, a naturally occurring enzyme, could potentially cause so-far-undiscovered side effects.


7 posted on 08/19/2009 9:43:32 AM PDT by neverdem (Xin loi minh oi)
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To: hellbender

Thanks for that backround history.


8 posted on 08/19/2009 9:47:03 AM PDT by neverdem (Xin loi minh oi)
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To: norraad
Enter squalene "skin cream" into a search engine. I have doubts about it being an enzyme, a long chain fatty acid, maybe.
9 posted on 08/19/2009 10:02:22 AM PDT by neverdem (Xin loi minh oi)
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To: norraad; All
Reactions of ozone with human skin lipids: Sources of carbonyls, dicarbonyls, and hydroxycarbonyls in indoor air

It appears that squalene is made by our skin.

10 posted on 08/19/2009 10:24:50 AM PDT by neverdem (Xin loi minh oi)
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To: Daffynition

>>> *Ping* Safrguns ...sounds like your territory

thanks...

yes, no doubt in my mind that this is true.
I can attest that at least in higher than normal atmospheric levels, Ozone IS an irritant to both the skin and lungs.
It will cause headaches too. (our lungs cannot absorb O3)
It is my understanding that it’s the 2nd strongest oxidant known.

As for by product chemical reactions, There is probably more that we don’t know about O3 reactions with other chemicals than what we do know. We are talking about free radicals of Oxygen here. I do know this... dont use it on wet carpets... O3 + H2O = Hydrogen Peroxide... it will bleach your carpets.

O3 is very unstable, and will shed an O1 fairly quickly to revert back to O2. (anywhere within minutes to several hours of being formed)

I use it for odor control in my business. It’s not a cure-all. You HAVE to remove the odor source with conventional cleaning methods first. But it does go where conventional cleaning methods wont.

I strongly recommend AGAINST using those home air purifiers that produce Ozone. If you have one, or want one, get a generator that produces a LOT of it... and then use it as a shock therapy tool in problem areas (while people/pets/plants are OUT!) instead of using it continuously as an air freshener... BAD!

Had a customer once who was suffering from headaches, spent 1200.00 at some mold inspection company which gladly came in his house and found mold for him (and recommended about 10,000 worth of repairs), and called me for an estimate to remove the mold.

I gave him the estimate, but noticed he had one of those generators... and after reviewing the mold testing results, suggested to him that his headaches and shortness of breath was coming from the ozone generator... not the mold.

Saved him about $10,000.


11 posted on 08/19/2009 12:41:04 PM PDT by Safrguns
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To: neverdem

Yes,, but should it be in that form in a vaccine in blood?


12 posted on 08/19/2009 2:55:44 PM PDT by norraad ("What light!">Blues Brothers)
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To: norraad; Squantos; vetvetdoug

http://www.anthrax.osd.mil/resource/qna/qaAll.asp?cID=319

I just found this looking for squalene in animal vaccines.


13 posted on 08/19/2009 3:37:30 PM PDT by neverdem (Xin loi minh oi)
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To: Safrguns

BTTT ;D


14 posted on 08/19/2009 3:41:16 PM PDT by Daffynition ("...... we are about to be czarred and fettered." ~ alterum ictum faciam.)
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