It might be interestign to review the list of US generalofficers who were relieved of their commands in the early days of WW II, starting with Kasserine Pass.
You might find some earlier than that. The early days around Guadalcanal was not the U.S. Navy's finest hour. For individual ship C.O.'s. I don't know about admirals.
Vice Admiral Robert Lee Ghormley, the commander of US naval forces in the South Pacific, had what can almost be described as a nervous breakdown while leading the defense of the waters around Guadalcanal. He became so convinced that the Japanese were going to steamroll his forces and obliterate the troops on Guadalcanal that he sent a series of extremely pessimistic messages to Pearl Harbor, demanding completely unrealistic reinforcements.
He was replaced in mid-October, 1942 by Vice Admiral William "Bull" Halsey, and spent the rest of the war in minor commands.