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Researchers identify the molecular target of J147...nearing clinical trials...Alzheimer's disease
medicalxpress.com ^ | January 9, 2018 | Salk Institute

Posted on 01/09/2018 12:49:23 PM PST by Red Badger

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1 posted on 01/09/2018 12:49:23 PM PST by Red Badger
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To: Red Badger

Juan Ponce de León smiles.


2 posted on 01/09/2018 12:52:42 PM PST by glock rocks (... so much win!)
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To: Red Badger
J147 is a modified version of a molecule found in the curry spice curcumin
3 posted on 01/09/2018 12:54:21 PM PST by Pelham (all warfare is based on deception)
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To: glock rocks

Move this right along, boys and girls. I am not getting any younger, yet.


4 posted on 01/09/2018 12:55:45 PM PST by Louis Foxwell (Islam is Satans finest work.)
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To: Red Badger

Bkmrk.


5 posted on 01/09/2018 12:57:25 PM PST by RushIsMyTeddyBear (Screw The NFL!!!!!! My family fought for the flag!)
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To: Pelham

I love curry!.......................the spice, not the basketball player................


6 posted on 01/09/2018 12:58:07 PM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: Louis Foxwell

Oddly, Pfizer just announced yesterday that they were DISCONTINUING research into Alzheimer’s and Parkinson’s medications...................hmmmmm..................


7 posted on 01/09/2018 12:59:40 PM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: Pelham

I take 30mg of curcumin daily.


8 posted on 01/09/2018 1:00:49 PM PST by glock rocks (... so much win!)
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To: Red Badger
Preventing Alzheimer’s with Turmeric?
9 posted on 01/09/2018 1:03:29 PM PST by Pelham (all warfare is based on deception)
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To: Pelham

I wonder what the prevalence of Alzheimer’s is among populations that eat lots of turmeric and curry foods their whole lives?....................


10 posted on 01/09/2018 1:17:37 PM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: Red Badger
Maybe this could work on people who suffer from Chronic Fatigue Syndrome?

Word is that they have a mitochondria disfunction which causes the oppressive fatigue.

11 posted on 01/09/2018 1:17:47 PM PST by Slyfox (Not my circus, not my monkeys)
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To: Slyfox

Or Fibromyalgia .................


12 posted on 01/09/2018 1:21:07 PM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: glock rocks

Do you buy it in capsules? Does it cause heartburn?


13 posted on 01/09/2018 1:23:08 PM PST by Excellence (Marine mom since April 11, 2014)
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To: Excellence

Yes, capsules. No heartburn.

https://www.amazon.com/gp/product/B00CJ71JCK/ref=oh_aui_search_detailpage?ie=UTF8&th=1


14 posted on 01/09/2018 1:38:36 PM PST by glock rocks (... so much win!)
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To: Red Badger
Yeah. There was another thread on how ibuprophan might cause testosterone problems.

I have often wondered if taking ibuprophan might be a cause of fibromyalgia.

15 posted on 01/09/2018 1:50:09 PM PST by Slyfox (Not my circus, not my monkeys)
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To: Red Badger

3% in rural India vs 19% in rural Pennsylvania

Rural India has the high turmeric/curry diet.


16 posted on 01/09/2018 1:50:53 PM PST by Pelham (all warfare is based on deception)
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To: Excellence; glock rocks

30 mg is not a high dose of curcumin. 400mg is a common dose in other products.

The lady who reportedly defeated her blood cancer with curcumin (https://www.thesun.co.uk/news/5258742/cancer-patient-67-beats-the-disease-with-the-help-of-turmeric-after-five-years-of-chemo-failed/), takes an exceptionally high dose of 8,000 mg (8 grams) per day.

Curcumin is also a powerful anti-inflamatory, if you have arthritis. It is a powerful anti-oxidant. 1,000 mg (1 gram) per day was shown to be as effective against depression as prozac.


17 posted on 01/09/2018 2:06:12 PM PST by BeauBo
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To: Pelham

“3% in rural India vs 19% in rural Pennsylvania”

Not to downplay the possibility that Turmeric and and Curry may have significant health benefits, but the average lifespan in rural India is late 60s versus late 70s in the USA.

This is also the age when symptoms of dementia become more prominent and diagnosable.


18 posted on 01/09/2018 2:10:35 PM PST by unlearner (You will never come to know that which you do not know until you first know that you do not know it.)
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To: Pelham; Red Badger

“3% (incidence of Alzheimer”s) in rural India vs 19% in rural Pennsylvania”

Life expectancy is much lower in rural India, so some number may just die of other causes, before they might have developed Alzheimer’s.

Notwithstanding any potential confounding factors with that, the results published in the Nature article are dynamite - Nobel Prize potential.


19 posted on 01/09/2018 2:11:58 PM PST by BeauBo
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To: BeauBo
Life expectancy is much lower in rural India, so some number may just die of other causes, before they might have developed Alzheimer’s.

That has already been accounted for in the calculation

20 posted on 01/09/2018 2:17:32 PM PST by Pelham (all warfare is based on deception)
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