Posted on 09/28/2022 6:09:30 AM PDT by DoodleBob
Circulating viruses, especially influenza A(H3N2) viruses, experience fast antigenic drift that necessitates vaccine reconfiguration. Since vaccination-induced protection against homologous strains may decrease, influenza vaccines must be administered afresh yearly.
In several nations, a yearly seasonal influenza vaccine is currently advised. However, repeated injections of vaccination may reduce its effectiveness.
About the study
In the present study, researchers conducted a thorough review and meta-analysis of trials reporting vaccine efficacy by vaccination status from the prior year.
Throughout this systematic review and meta-analysis, the team adhered to PRISMA standards. For publications published between January 1, 2016, and June 13, 2022, the databases MEDLINE, EMBASE, and CINAHL were searched. For research published in English between the beginning of the database and June 13, 2022, the team searched the Web of Science. Additionally, the team looked through reference lists and MEDLINE, EMBASE, and CINAHL Complete databases for non-English language research until December 31, 2015.
Four comparison groups, including vaccinations administered in the present season only, the previous season, the current season and the previous season, and neither season were created. Observational studies and randomized controlled trials that reported vaccine efficacy against laboratory-confirmed influenza were reported. Two reviewers carried out screening, data extraction, and risk of bias analyses separately. Extracted information comprised research, patient characteristics, and odds ratio estimates for each season's vaccination efficacy according to age group and type of influenza virus.
The absolute difference in vaccine efficacy (VE) between those who received vaccinations during the current and prior seasons (VECP) and those who received vaccinations solely during the current season (VEC) was estimated. If inoculated during the current and past seasons and not in the current season, VE more than zero suggests greater vaccine efficacy. By season and age group for each vaccination group, the team calculated pooled vaccine efficacy for influenza A(H1N1), influenza A(H3N2), and influenza B.
...
According to the majority of estimations, those who received vaccinations during the present season and past seasons had significantly higher vaccine effectiveness than those who received vaccinations solely during the current season.
Estimates of combined vaccine efficacy against influenza A (H3N2) were poor compared to those for other types like A subtypes or B lineages. Vaccine efficacy for the current season only group was 37%, for the current season and the previous season group was 20%; and for the previous season only group was 9%. Except for 2013–14, estimates of the seasonal pooled vaccination effectiveness for the current and prior season groups were lower than those for the current season only group. In both the current and prior season groups, the reduced season-specific pooled vaccine efficacy estimates were most prominent in 2014–15.
Conclusion
The study findings showed that vaccination administered against influenza in two consecutive years offered greater protection as compared to when no vaccine was administered, even though vaccination in the year prior reduces the effectiveness of the vaccine. However, the estimated effects of vaccination received in the prior year are not consistent or severe enough to recommend a different vaccination strategy at this time.
I can believe that. Back in the 1990s I got the flu shot every fall. Due to a severe reaction in the late 90s I stopped getting the shot. I noticed that previously I would get lung infections 4 to 5 times a year, usually bronchitis. A few years after stopping the flu shots, I pretty much stopped getting lung infections. Now I only get pleurisy every few years and colds even less.
it doesn’t “reduce its effectiveness”: it rapidly drags people down to negative efficacy and dread ultimate effects, including death.
In the world of software, that’s called an “undocumented feature.”
Long term, I do not know the answer, but annual flu efficacy is usually in the 40%-50% range, which is interesting since they completely whiff on at least one of viruses they select each year.
Also, within the last month, I read that people who get the flu vaccine every year (like me) have almost the same risk for Covid infection as the people who get the Covid booster.
I am glad they are doing these studies and publishing results. I suspect they never want to be honest with people, they think we are stupid (Fauci is a great example).
They refrain from saying that flu vaccines may be 20 or 30 or maybe 40% effective thinking people will not get them. Instead, they should tell people that the vaccinations can reduce the severity - which in and of itself should be an incentive.
But instead they obfuscate and over sell and market and never simply level with the American people. This is why I so distrust the elite class, they think they are always smarter than everyone else and then what they do is much harm to everyone else - classic example, shutting down the economy.
I stopped getting the flu shot and do not see any changes to my coming down with sinus issues.
Health ping
My wife is a retired research scientist who worked on influenza vaccines. Long before the covud madness she had told me how each years flu shot was formulated against the particular strains that were suspected of becoming the dominant ones in the coming season. Sometimes they guessed wrong and it was not very effective because a different strain would be dominant.
FAUDci, himself, admitted this, years ago.
I see the same. My sinus allergies have not gotten better. This year they seem particularly bad. The pine pollen is horrible for me.
Sister and I both in our 80’s. All her life she would be at the doctor office any time she got a sniffle. She was always having prescriptions to fill. Her medicine cabinet quickly became a medicine closet/room. Later becoming several different prescriptions taken simultaneously. When flu shots started becoming available, she never missed one. Covid shots...check.
Me. Totally the opposite. See the doctor every 5 years or so like our Dad who lived to nearly 100. Tylenol is my go-to. Never had the flu shot. Never the Covid shot. Been on fish oil, Vit C and D3 for nearly 20 years.
I have always lived an active lifestyle, and still do. Rarely get a cold/flu. When I do I get over it quickly without doctors/prescriptions. Sister had to give up driving 20 years ago and has a dependency on her children.
Oh yeah, building a new house and getting married in November. Life is what you make of it.
Long term, I do not know the answer, but annual flu efficacy is usually in the 40%-50% range, which is interesting since they completely whiff on at least one of viruses they select each year.
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A case can be made for playing the odds. Even if the efficacy is that low, 40%-50% is better than the 0% from not taking the shot, especially if the strain is particularly nasty.
When I was a heavy smoker I caught a cold twice a year. Not one since I quit decades ago. Also, I’ve never had a flu shot. Coincidentally I have never had the flu.
You talkin’ traditional bugs—or intel agency back doors?
Yah, since all of the real vaccine development (not mRNA crappola) got offshored only 6 strains are “guessed”. If you miss the one that really comes to pass — everyone loses - except those that got paid in gov’mt $$.
“Circulating viruses, especially influenza A(H3N2) viruses, experience fast antigenic drift that necessitates vaccine reconfiguration.
Since vaccination-induced protection against homologous strains may decrease, influenza vaccines must be administered afresh yearly.
In several nations, a yearly seasonal influenza vaccine is currently advised.
However, repeated injections of vaccination may reduce its effectiveness. “
”According to the majority of estimations, those who received vaccinations during the present season and past seasons had significantly higher vaccine effectiveness than those who received vaccinations solely during the current season. “
”Estimates of combined vaccine efficacy against influenza A (H3N2) were poor compared to those for other types like A subtypes or B lineages.
Vaccine efficacy for the current season only group was 37%,
for the current season and the previous season group was 20%;
and for the previous season only group was 9%. “
(My Comment) : While this study reflects on influenza vaccinations,
might a similar response have been experienced by those covid vaccinations and boosters ?
It seems possible, if not likely, given current reports.
I have a sister who, along with her adult daughter, had/has had the fly vaccine, religiously, year after year, while I have never had the flu vaccine since the military over 50 years ago. They both have major URIs every flu season and their stupid health care provider (Kaiser) does not even test them for flu (and will only if they need hospitalization). While I have never had the flu, unless it was so asymptomtic as to appear to be a minor alergy related head cold.
The CDC has never published ANY STUDY showing the actual efficacy of flu vaxes. All they show is antibodies or something after the vax. A study could easily be done thusly:
After the flu season check a number of vaxed personsm say 5000, various demographics to see if they got the flu.
Check a similar number and demographics group that did not get the vax, and see if they got flu.
The groups would need to be arranged before flu season of course, and told that any who felt sick go to Dr and get tested for flu.
Easy peasy, even a high school dropout like me can figure this out. But they have never done this, or if so, never publicized the results.
The CDC exists to sell vaxes.
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