[ConservativeMind]

Beta carotene was the only supplement to increase all cause mortality.

Lots of positive supplements to help are listed in there.

[ConservativeMind]

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[nickcarraway]

It’s interesting, because in the 1990s there was a study that said beta-carotene increase the risk of cancer. I assume that getting beta-carotene in food does not do that.

[nickcarraway]

I should have said that I have heard some people suggest that supplements like beta-carotene that are found to increase rather than decrease risk do so because the form in some supplements is not the optimal form.

[joshua c]

omega 6 was bad

[joshua c]

i thought omega 6 was bad

[EEGator]

I think “L-arginine” can have an issue with BP meds.
I know that arginine and nitric oxide are often in pre-workout supplements.
(B-vitamins, caffeine, and niacin as well)

[xp38]

Vitamins C D and E showed no cardio benefit. Well fine but there are a lot of other problems we humans have that those might help. D especially during these covid times we live in.

[gawatchman]

bkmk

[tired&retired]

This is a super meta-analysis.

On the surface it is excellent. But one must dig much deeper to understand “WHY” and not just accept it as truth.

I am especially puzzled by the beta carotene correlation.

[sauropod]

.

[9YearLurker]

So hard to tell with such studies, as they are a mishmash of pharma-funded to discredit low-cost, unpatented supplements, poorly controlled for confounding factors, uselessly high or low dosages, short duration or poor follow up, etc., etc.

Most reported results here are just for CV outcomes, but then some all-cause mortality woven in.

[MarMema]

Thank you again.

[kelly4c]

Bkmk

[ckilmer]

Two of these were not quite clear to me: flavanol and genistein.

With flavanol you think of the color in fruits and vegetables but not a particular supplement. Is there such a thing as a flavanol supplement?

I’ve never heard of genistein. What is it?

[Vision]

It’s hard to believe beta carotene is bad for you. Especially since it’s often part of the blue zone diet.

[The Truth Will Make You Free]

Vitamin C, Vitamin D, Vitamin E and selenium showed no effect on long-term cardiovascular disease outcomes

OK, but don't leave them hanging like their no good. C D and Selenium strengthen the immune system.

[spankalib]

I think we should take supplements that contain carotenoids - as many carotenoids as possible - not just one (isolated) beta carotene.

Same with the B's - they should be taken together.

It's something to consider...

(but if carrots are so good for the eyes, how come there's so many dead bunnies on the road?)